FlyBase Allele Report: Dmel\sd[EP1435]

General Information

Symbol

Dmel\sd^EP1435

Species

D. melanogaster

Name

FlyBase ID

FBal0088662

Feature type

allele

Associated gene

Dmel\sd

Associated Insertion(s)

P{EP}sd^EP1435

Carried in Construct

Key Links

Genomic Maps

JBrowse

Allele class

Mutagen

P-element activity

Nature of the Allele

Allele class

Mutagen

P-element activity

(Rorth et al., 1998)

Progenitor genotype

Associated Insertion(s)

P{EP}sd^EP1435

Cytology

Description

P{EP} insertion 1297bp upstream of the sd translation initiation codon. The P{EP} element is oriented such that expression from the element should result in overexpression of sd.

(Bidet et al., 2003)

P{EP} insertion at +384bp of the transcription unit, 5' of the CDS.

(Abdelilah-Seyfried et al., 2000)

Allele components

Component

Use(s)

Inserted element

P{EP}

misexpression element

Regulatory region(s)

UAS

binary expression system - regulatory region

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

transposable_element_insertion_site

X:15,811,624..15,811,624 [+]

(Bidet et al., 2003, Pena-Rangel et al., 2002, Gene Disruption Project members, 2001-, Abdelilah-Seyfried et al., 2000, Rorth et al., 1998)

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

visible, with Scer\GAL4^ap-md544

(Pena-Rangel et al., 2002)

visible, with Scer\GAL4^sca-537.4

(Abdelilah-Seyfried et al., 2000)

Phenotype Manifest In

macrochaeta | ectopic, with Scer\GAL4^sca-537.4

(Abdelilah-Seyfried et al., 2000)

microchaeta, with Scer\GAL4^ap-md544

(Pena-Rangel et al., 2002)

microchaeta, with Scer\GAL4^sca-537.4

(Abdelilah-Seyfried et al., 2000)

Detailed Description

Statement

Reference

Expression of sd^EP1435 under the control of Scer\GAL4^ap-md544 results in loss of several microchaetae.

(Pena-Rangel et al., 2002)

Expression of sd^EP1435 under the control of Scer\GAL4^sca-537.4 results in additional macrochaetae and the loss of a few microchaetae on the notum.

(Abdelilah-Seyfried et al., 2000)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

NOT Enhanced by

Statement

Reference

Scer\GAL4^sca-537.4, sd^EP1435 has visible phenotype, non-enhanceable by H[+]/H^E21

(Abdelilah-Seyfried et al., 2000)

NOT suppressed by

Statement

Reference

Scer\GAL4^sca-537.4, sd^EP1435 has visible phenotype, non-suppressible by H[+]/H^E21

(Abdelilah-Seyfried et al., 2000)

Enhancer of

Statement

Reference

Scer\GAL4^pnr-MD237/sd^EP1435 is an enhancer of visible phenotype of pnr^MD237

(Pena-Rangel et al., 2002)

Phenotype Manifest In

Enhancer of

Statement

Reference

Scer\GAL4^pnr-MD237/sd^EP1435 is an enhancer of chaeta phenotype of pnr^MD237

(Pena-Rangel et al., 2002)

NOT Enhancer of

Statement

Reference

sd^EP1435/Scer\GAL4^sca-537.4 is a non-enhancer of phenotype of H^E21

(Abdelilah-Seyfried et al., 2000)

NOT Suppressor of

Statement

Reference

sd^EP1435/Scer\GAL4^sca-537.4 is a non-suppressor of phenotype of H^E21

(Abdelilah-Seyfried et al., 2000)

Other

Statement

Reference

Scer\GAL4^pnr-MD237, pnr^MD237, sd^EP1435 has dorsocentral bristle phenotype

(Pena-Rangel et al., 2002)

Scer\GAL4^pnr-MD237, pnr^MD237, sd^EP1435 has microchaeta phenotype

(Pena-Rangel et al., 2002)

Scer\GAL4^pnr-MD237, pnr^MD237/pnr[+], sd^EP1435 has dorsocentral bristle phenotype

(Pena-Rangel et al., 2002)

Scer\GAL4^pnr-MD237, pnr^MD237/pnr[+], sd^EP1435 has microchaeta phenotype

(Pena-Rangel et al., 2002)

Additional Comments

Genetic Interactions

Statement

Reference

pnr^MD237/+ adults expressing sd^EP1435 under the control of Scer\GAL4^pnr-MD237 show loss of several microchaetae and dorsocentral macrochaetae.

(Pena-Rangel et al., 2002)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

Selected as: a P{EP} insertion line that modifies the pnr^MD237/+ phenotype when expressed using Scer\GAL4^pnr-MD237.

(Pena-Rangel et al., 2002)

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

EP(X)1435

(Abdelilah-Seyfried et al., 2000)

sd^EP1435

Name Synonyms

Secondary FlyBase IDs

References (5)

Report Sections

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