FB2024_03 , released June 25, 2024
Allele: Dmel\crbunspecified
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General Information
Symbol
Dmel\crbunspecified
Species
D. melanogaster
Name
FlyBase ID
FBal0086672
Feature type
allele
Associated gene
Dmel\crb
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
ethyl methanesulfonate
(Moore et al., 1998)
Progenitor genotype
Cytology
Description
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      The apical zonula adherens is missing in crbunspecified embryos. It is restored by the addition of crbintra.Scer\UAS.T:Hsap\MYC driven by Scer\GAL4385.3.

      (Klebes and Knust, 2000)

      Embryos exhibit defects in cellular differentiation.

      (Moore et al., 1998)

      Embryos have many small holes in the cuticle, and hypertrophy of the ventral nervous system.

      (Tearle and Nusslein-Volhard, 1987)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Enhancer of
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      The cuticle defects seen at 20[o]C in embryos derived from exo84onr/Df(3R)Espl3 females mated to exo84onr heterozygous males are enhanced by crbunspecified.

      (Blankenship et al., 2007)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      Comments
      Comments

      2 mutants are isolated.

      (Moore et al., 1998)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      crbunspecified
      Name Synonyms
      Secondary FlyBase IDs
        References (7)