FB2024_03 , released June 25, 2024
Allele: Dmel\btlΔOh10
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General Information
Symbol
Dmel\btlΔOh10
Species
D. melanogaster
Name
FlyBase ID
FBal0083056
Feature type
allele
Associated gene
Dmel\btl
Associated Insertion(s)
P{?lacW}btlΔOh10
Carried in Construct
Key Links
Allele class

amorphic allele - molecular evidence

Mutagen
Nature of the Allele
Allele class

amorphic allele - molecular evidence

(Ohshiro and Saigo, 1997)
Mutagen
P-element activity
(Ohshiro and Saigo, 1997)
Progenitor genotype
btl6-81
(Ohshiro and Saigo, 1997)
Associated Insertion(s)
P{?lacW}btlΔOh10
Cytology
Description

Imprecise excision of the P{lacW} element, deleting the entire btl coding region.

(Ohshiro and Saigo, 1997)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      No sign of primary tracheal branching is seen in btlΔOh10 embryos.

      (Ikeya and Hayashi, 1999)

      Elongated tracheal sacs from which hardly any primary branches grow are seen in homozygous embryos.

      (Ohshiro and Saigo, 1997)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Enhancer of
      Statement
      Reference

      btl[+]/btlΔOh10 is an enhancer of dorsal group tracheal branch precursor phenotype of Rac1J11, Rac2Δ/Rac2[+]

      (Chihara et al., 2003)

      btl[+]/btlΔOh10 is an enhancer of tracheal branch primordium phenotype of Rac1J11, Rac2Δ/Rac2[+]

      (Chihara et al., 2003)

      btl[+]/btlΔOh10 is an enhancer of tracheal dorsal trunk primordium phenotype of Rac1J11, Rac2Δ/Rac2[+]

      (Chihara et al., 2003)
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescued by

      btlΔOh10 is rescued by btlABP

      (Ohshiro and Saigo, 1997)

      btlΔOh10 is rescued by btlN-14

      (Ohshiro and Saigo, 1997)
      Comments

      The homozygous lethality and tracheal defects are rescued by btlN-14 and btlABP.

      (Ohshiro and Saigo, 1997)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      btldeltaOh10
      (Kondo and Hayashi, 2019)
      btlΔOh10
      (Kondo and Hayashi, 2013)
      Name Synonyms
      Secondary FlyBase IDs
        References (6)