FlyBase Allele Report: Dmel\Mmp1[k04809]

(Kanda et al., 2019, Azpurua et al., 2018, Rudrapatna et al., 2014, Page-McCaw et al., 2003, Spradling et al., 1999, BDGP Project Members, 1994-1999)

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

lethal | recessive

(Spradling et al., 1999, BDGP Project Members, 1994-1999)

Phenotype Manifest In

embryonic/larval posterior spiracle

(Page-McCaw et al., 2003)

embryonic/larval tracheal dorsal trunk

(Page-McCaw et al., 2003)

Detailed Description

Statement

Reference

Neuromuscular abnormalities are not observed in mutant larvae.

(Meyer and Aberle, 2006)

Third instar Mmp1^k04809 larvae have abnormal posterior spiracles and dorsal trunk constrictions.

(Page-McCaw et al., 2003)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Other

Statement

Reference

Csk^GD9345, Mmp1^k04809/Mmp1[+], Scer\GAL4^ptc-559.1 has abnormal cell migration phenotype

(Rudrapatna et al., 2014)

Csk^GD9345, Mmp1^k04809/Mmp2^EY08942 has lethal phenotype

(Rudrapatna et al., 2014)

Phenotype Manifest In

Other

Statement

Reference

Csk^GD9345, Mmp1^k04809/Mmp1[+], Scer\GAL4^ptc-559.1 has wing disc phenotype

(Rudrapatna et al., 2014)

Additional Comments

Genetic Interactions

Statement

Reference

A Mmp1^k04809 heterozygous mutant background modifies the actin remodelling and subsequent basolateral invasion of epithelial cells seen in flies expressing Csk^GD9345 in a stripe of cells at the anterior/posterior boundary of the larval wing disc under the control of Scer\GAL4^ptc-559.1.

(Rudrapatna et al., 2014)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (2)

Bloomington

12205

y¹ w^67c23; P{lacW}Mmp1^k04809/CyO

Kyoto

111451

y^d2 w¹¹¹⁸ P{ey-FLP.N}2 P{5xglBS-lacZ.38-1}TPN1; P{neoFRT}42D P{lacW}Mmp1^k04809 /CyO y⁺

Notes on Origin

Discoverer

I. Kiss.

(BDGP Project Members, 1994-1999)

Comments

Complements: Dll⁰¹⁰⁹². Complements: l(2)k00808^k00808.

(BDGP Project Members, 1994-1999)

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (5)

Reported As

Symbol Synonym

Mmp1^k04809

(Rudrapatna et al., 2014, Christensen et al., 2008.9.3, Meyer and Aberle, 2006)

Mmp1^l(2)k04809

(Page-McCaw et al., 2003)

l(2)k04809

(Page-McCaw et al., 2003, Spradling et al., 1999)

l(2)k04809^k04809

(BDGP Project Members, 1994-1999)

mmp1^k04809

(Kanda et al., 2019)

Name Synonyms

Secondary FlyBase IDs

References (8)

Report Sections

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