FlyBase Allele Report: Dmel\Ubc2[k13206]

General Information

Symbol

Dmel\Ubc2^k13206

Species

D. melanogaster

Name

FlyBase ID

FBal0064146

Feature type

allele

Associated gene

Dmel\Ubc2

Associated Insertion(s)

P{lacW}Ubc2^k13206

Carried in Construct

Also Known As

l(2)k13206

Key Links

Genomic Maps

JBrowse

Allele class

Mutagen

P-element activity

Nature of the Allele

Allele class

Mutagen

P-element activity

(BDGP Project Members, 1994-1999)

Progenitor genotype

Associated Insertion(s)

P{lacW}Ubc2^k13206

Cytology

Description

Allele components

Component

Use(s)

Inserted element

P{lacW}

enhancer trap

Encoded product / tool

lacZ

reporter enzyme

Tagged with

Tag:NLS(P)

nuclear protein localization tag

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

transposable_element_insertion_site

2L:10,767,810..10,767,817 [-]

(Kuo et al., 2006, Watts et al., 2003, Mesilaty-Gross et al., 1999, Spradling et al., 1999, BDGP Project Members, 1994-1999)

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal neuroanatomy | somatic clone

(Watts et al., 2003)

lethal | recessive

(Spradling et al., 1999, BDGP Project Members, 1994-1999)

Phenotype Manifest In

neuroblast | somatic clone

(Watts et al., 2003)

Detailed Description

Statement

Reference

UbcD2^k13206 mutant C4da neuronal clones do not exhibit defects in dendrite pruning or neuronal cell death 18-20 hours after puparium formation.

(Kuo et al., 2006)

No defects are seen in axon pruning during metamorphosis, though moderate axon misguidance is seen when somatic clones are made in the neuroblast.

(Watts et al., 2003)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhancer of

Statement

Reference

Ubc2^k13206/UbcD2[+] is an enhancer of abnormal mitotic cell cycle phenotype of enc^unspecified

(Ohlmeyer and Schupbach, 2003)

NOT Enhancer of

Statement

Reference

Ubc2^k13206/UbcD2[+] is a non-enhancer of visible | dominant phenotype of gcm^Pyx

(Popkova et al., 2012)

NOT Suppressor of

Statement

Reference

Ubc2^k13206/UbcD2[+] is a non-suppressor of visible | dominant phenotype of gcm^Pyx

(Popkova et al., 2012)

Phenotype Manifest In

Enhancer of

Statement

Reference

Ubc2^k13206/UbcD2[+] is an enhancer of egg chamber phenotype of enc^unspecified

(Ohlmeyer and Schupbach, 2003)

NOT Enhancer of

Statement

Reference

Ubc2^k13206/UbcD2[+] is a non-enhancer of chaeta | increased number phenotype of gcm^Pyx

(Popkova et al., 2012)

Ubc2^k13206 is a non-enhancer of phenotype of rpr^GMR.PW

(Ryoo et al., 2002)

Ubc2^k13206 is a non-enhancer of phenotype of hid^GMR.PG

(Ryoo et al., 2002)

Ubc2^k13206 is a non-enhancer of phenotype of Diap1^RING.GMR

(Ryoo et al., 2002)

NOT Suppressor of

Statement

Reference

Ubc2^k13206/UbcD2[+] is a non-suppressor of chaeta | increased number phenotype of gcm^Pyx

(Popkova et al., 2012)

Ubc2^k13206 is a non-suppressor of phenotype of hid^GMR.PG

(Ryoo et al., 2002)

Ubc2^k13206 is a non-suppressor of phenotype of rpr^GMR.PW

(Ryoo et al., 2002)

Ubc2^k13206 is a non-suppressor of phenotype of Diap1^RING.GMR

(Ryoo et al., 2002)

Additional Comments

Genetic Interactions

Statement

Reference

The extra mitotic division phenotype seen in the egg chambers of enc^unspecified females is enhanced by one copy of UbcD2^k13206 at both room temperature and 25^oC; the frequency of egg chambers containing 32 cells is increased in the double mutant females.

(Ohlmeyer and Schupbach, 2003)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (2)

Bloomington

11071

y¹ w^67c23; P{lacW}Ubc2^k13206/CyO

Kyoto

111318

y^d2 w¹¹¹⁸ P{ey-FLP.N}2 P{5xglBS-lacZ.38-1}TPN1; P{lacW}Ubc2^k13206 P{neoFRT}40A/CyO y⁺

Notes on Origin

Discoverer

I. Kiss.

(BDGP Project Members, 1994-1999)

Comments

Complements: porin^k05123. Complements: l(2)k09015a^k09015a. Complements: Fatp^k10307.

(BDGP Project Members, 1994-1999)

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (5)

Reported As

Symbol Synonym

Ubc2^k13206

UbcD2^k13206

(Christensen and Cook, 2006.8.30)

l(2)k13206

(Mesilaty-Gross et al., 1999, Spradling et al., 1999)

l(2)k13206^k13206

(BDGP Project Members, 1994-1999)

ubcD2^k13206

(Ryoo et al., 2002)

Name Synonyms

Secondary FlyBase IDs

References (10)

Report Sections

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