FB2024_03 , released June 25, 2024
Allele: Dmel\Khck13219
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General Information
Symbol
Dmel\Khck13219
Species
D. melanogaster
Name
FlyBase ID
FBal0064142
Feature type
allele
Associated gene
Dmel\Khc
Associated Insertion(s)
P{lacW}Khck13219
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
P-element activity
(BDGP Project Members, 1994-1999)
Progenitor genotype
Associated Insertion(s)
P{lacW}Khck13219
Cytology
Description
Allele components
Component
Use(s)
Inserted element
P{lacW}
Encoded product / tool
lacZ
Tagged with
Tag:NLS(P)
Mutations Mapped to the Genome
Curation Data
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Khck13219 mutant germline clones show oocyte mislocalisation.

      (Kucherenko et al., 2008)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Suppressor of
      Statement
      Reference

      Khck13219/Khc[+] is a suppressor of visible phenotype of DysRNAi.C.UAS, Scer\GAL4Tub.PU

      (Kucherenko et al., 2008)
      Phenotype Manifest In
      Suppressor of
      Statement
      Reference

      Khck13219/Khc[+] is a suppressor of posterior crossvein phenotype of DysRNAi.C.UAS, Scer\GAL4Tub.PU

      (Kucherenko et al., 2008)

      Khck13219/Khc[+] is a suppressor of eye photoreceptor cell & nucleus phenotype of DCTN1-p150Gl-1

      (Whited et al., 2004)

      Khck13219/Khc[+] is a suppressor of eye phenotype of DCTN1-p150Gl-1

      (Whited et al., 2004)

      Khck13219/Khc[+] is a suppressor of ommatidium phenotype of DCTN1-p150Gl-1

      (Whited et al., 2004)
      Other
      Statement
      Reference

      DysRNAi.C.UAS, Khck13219/Khc[+] has wing vein | ectopic phenotype

      (Kucherenko et al., 2008)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      One copy of Khck13219 moderately suppresses the detached posterior crossvein phenotype seen when DysdsRNA.C.Scer\UAS is expressed under the control of Scer\GAL4tub.PU but produces extra wing vein material.

      (Kucherenko et al., 2008)

      The Gl1/+ adult eye phenotype and the loss of photoreceptor nuclei from the retina in late third instar Gl1/+ larvae are partially suppressed by Khck13219/+.

      (Whited et al., 2004)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (2)
      Notes on Origin
      Discoverer

      I. Kiss.

      (BDGP Project Members, 1994-1999)
      Comments
      Comments

      This allele was listed in the BDGP database as a lethal or sterile line during the period 1994-1999, but was discarded from the gene disruption project prior to the summary publication (FBrf0111489). Reasons for excluding lines from the collection described in FBrf0111489 include presence of more than one P insertion on the mutant chromosome, separation of lethality (or sterility) from the location of the insertion, and loss of lethality (or sterility) from the stock. Further information is available from http://www.fruitfly.org/bfd/ and from Dr. Spradling (spradling@mail1.ciwemb.edu).

      Complements: l(2)02836a02836a. Complements: l(2)k0650202839. Complements: l(2)02836ak05440. Complements: Lis-1k13209. Complements: l(2)02836ak14103.

      (BDGP Project Members, 1994-1999)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Khck13219
      (Kucherenko et al., 2008)
      l(2)k13219k13219
      (BDGP Project Members, 1994-1999)
      Name Synonyms
      Secondary FlyBase IDs
        References (3)