FB2024_03 , released June 25, 2024
Allele: Dmel\Src64BΔ540.hs.sev
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General Information
Symbol
Dmel\Src64BΔ540.hs.sev
Species
D. melanogaster
Name
FlyBase ID
FBal0063063
Feature type
allele
Associated gene
Dmel\Src64B
Associated Insertion(s)
Carried in Construct
P{Δ540}
Key Links
Transgenic product class
inframe_deletion
(Cooper et al., 1996)
Mutagen
Nature of the Allele
Transgenic product class
inframe_deletion
(Cooper et al., 1996)
Mutagen
in vitro construct
(Cooper et al., 1996)
Progenitor genotype
Carried in construct
P{Δ540}
Cytology
Description

Expression of Src64B truncated at residue 540 is under the control of an Hsp70 promoter and tandem 1.2kb XhoI fragment containing the enhancer element from the first intron of sev.

(Cooper et al., 1996)
Allele components
Component
Use(s)
Regulatory region(s)
Hsp70
sev
Encoded product / tool
Src64B
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Rough eye phenotype; ommatidia contain a variable number of R7 cells.

      (Cooper et al., 1996)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Suppressed by
      Statement
      Reference

      Src64BΔ540.hs.sev has visible phenotype, suppressible by cswEsev1A-eOP/csw[+]

      (Cooper et al., 1996)

      Src64BΔ540.hs.sev has visible phenotype, suppressible by drk[+]/drke0A

      (Cooper et al., 1996)
      Phenotype Manifest In
      Suppressed by
      Statement
      Reference

      Src64BΔ540.hs.sev has eye phenotype, suppressible by cswEsev1A-eOP/csw[+]

      (Cooper et al., 1996)

      Src64BΔ540.hs.sev has eye phenotype, suppressible by drk[+]/drke0A

      (Cooper et al., 1996)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Individuals that carry cswEsev1A-eOP or drke0A exhibit reduced levels of eye roughening.

      (Cooper et al., 1996)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      Src64BΔ540.hs.sev
      Name Synonyms
      Secondary FlyBase IDs
        References (1)