FB2024_03 , released June 25, 2024
Allele: Ecol\lacZeg-P289
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General Information
Symbol
Ecol\lacZeg-P289
Species
E. coli
Name
FlyBase ID
FBal0062620
Feature type
allele
Associated gene
Ecol\lacZ
Associated Insertion(s)
P{lArB}egP289
Carried in Construct
Also Known As
Eg-lacZ
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
P-element activity
(Dittrich et al., 1997)
Progenitor genotype
Associated Insertion(s)
P{lArB}egP289
Cytology
Description
Allele components
Component
Use(s)
Inserted element
P{lArB}
Encoded product / tool
lacZ
Tagged with
Tag:NLS(P)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      distribution deduced from reporter
      Stage
      Tissue/Position (including subcellular localization)
      Reference
      embryonic stage 11
      neuroblast NB7-3
      (Lundell et al., 2003)
      serotonergic neuron | precursor
      (Lundell and Hirsh, 1998)
      neuroblast | subset
      (Badenhorst, 2001)
      embryonic stage 12 -- 16
      embryonic GW neuron
      (Lundell et al., 2003)
      embryonic stage 12 -- 17
      larval EW neuron
      (Lundell et al., 2003)
      embryonic stage 15 -- 17
      EW3 neuron
      (Lundell et al., 2003, Dittrich et al., 1997)
      EW2 neuron
      (Lundell et al., 2003, Dittrich et al., 1997)
      EW1 neuron
      (Lundell et al., 2003, Dittrich et al., 1997)
      embryonic GW neuron
      (Lundell et al., 2003, Dittrich et al., 1997)
      embryonic stage 16
      serotonergic neuron
      (Couch et al., 2004)
      embryonic stage 17
      EW1 neuron
      (Lundell and Hirsh, 1998)
      EW2 neuron
      (Lundell and Hirsh, 1998)
      EW3 neuron
      (Lundell and Hirsh, 1998)
      first instar larval stage
      serotonergic neuron | subset
      (Lundell and Hirsh, 1998)
      larval serotonergic VNC neuron | subset
      (Lundell and Hirsh, 1998)
      larval ventral nerve cord | restricted
      (Lundell and Hirsh, 1998)
      Additional Information
      Statement
      Reference

      Markers that uniquely identify the cells of the NB3-7 lineage were used to examine the serotonin expressing cell lineages.

      (Lundell et al., 2003)

      EcollacZeg-P289 is expressed in ventrolateral cell clusters of the ventral nerve cord. These clusters contain the ventrolateral serotonergic neurons. EcollacZeg-P289 is also expressed in small groups of cells lying close to the midline in each hemisegment. Many of these cells are serotonergic cells..

      (Lundell and Hirsh, 1998)
       
      Marker for
      abdominal neuroblast NB2-4
      (Dittrich et al., 1997)
      abdominal neuroblast NB6-4
      (Dittrich et al., 1997)
      embryonic GW neuron
      (Lundell et al., 2003)
      larval EW neuron
      (Lundell et al., 2003)
      neuroblast NB3-3
      (Dittrich et al., 1997)
      neuroblast NB7-3
      (Lundell et al., 2003, Dittrich et al., 1997)
      serotonergic neuron
      (Couch et al., 2004, Lundell and Hirsh, 1998)
      Reflects expression of
      eg
      (Couch et al., 2004, Lundell et al., 2003, Badenhorst, 2001, Lundell and Hirsh, 1998, Dittrich et al., 1997)
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      Ecol\lacZeg-P289
      eg289
      (Lee and Lundell, 2007)
      lacZeg-P289
      Name Synonyms
      Secondary FlyBase IDs
        References (10)