FlyBase Allele Report: Dmel\ph-p[602]

General Information

Symbol

Dmel\ph-p⁶⁰²

Species

D. melanogaster

Name

FlyBase ID

FBal0059975

Feature type

allele

Associated gene

Dmel\ph-p

Associated Insertion(s)

Carried in Construct

Also Known As

ph⁶⁰²

Key Links

Allele class

Mutagen

X ray

Nature of the Allele

Allele class

Mutagen

X ray

(Boivin et al., 1999, Fauvarque et al., 1995)

Progenitor genotype

Cytology

Description

Complex rearrangement in ph-p.

(Boivin et al., 1999)

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal eye color

(Fauvarque et al., 1995)

abnormal neuroanatomy | somatic clone

(Wang et al., 2006)

visible | adult stage

(Gibert et al., 2011)

Phenotype Manifest In

adult optic lobe neuron | somatic clone

(Wang et al., 2006)

antennal lobe | somatic clone

(Wang et al., 2006)

ellipsoid body | somatic clone

(Wang et al., 2006)

eye

(Gibert et al., 2011, Fauvarque et al., 1995)

Kenyon cell | somatic clone

(Wang et al., 2006)

lobula columnar neuron LC14 | somatic clone

(Wang et al., 2006)

Detailed Description

Statement

Reference

ph-p⁶⁰² ph-d⁴⁰¹ double heterozygous flies in a Df(4)ED6366 background have a much darker and more uniform eye colour than in Df(4)ED6366 alone.

(Gibert et al., 2011)

ph-p⁶⁰² clones induced in brains show a normal complement of neurons at the wandering larval stage, but around 1-2 days APF the neuron clones become transformed into unrecognizable neurons of a homogeneous nature. Ecdysone is required for this transformation as it is not observed when ph-p⁶⁰² mosaic brains are cultured in the absence of 20-hydroxyecdysone.

(Wang et al., 2006)

Mutation changes the level of w expression in ph-p^lac+3 flies; eye colour is darker.

(Fauvarque et al., 1995)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Other

Statement

Reference

Pc⁵, ph-d⁴⁰¹, ph-p⁶⁰² has visible | dominant | homeotic phenotype

(Boivin et al., 1999)

Pc⁵, ph-d⁴⁰¹, ph-p⁶⁰² has visible | homeotic phenotype

(Boivin et al., 1999)

Phenotype Manifest In

Other

Statement

Reference

Pc⁵, ph-d⁴⁰¹, ph-p⁶⁰² has wing | posterior phenotype

(Boivin et al., 1999)

Additional Comments

Genetic Interactions

Statement

Reference

ph-p⁶⁰² ph-d⁴⁰¹; Pc⁵/+ flies show a weak wing to haltere transformation.

(Boivin et al., 1999)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (2)

Bloomington

5444

ph-d⁴⁰¹ ph-p⁶⁰² w¹/FM7c, sn⁺

Kyoto

108238

ph-d⁴⁰¹ ph-p⁶⁰² w¹/FM7c

Notes on Origin

Discoverer

Induced on: ph-d⁴⁰¹.

(Boivin et al., 1999)

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (4)

Reported As

Symbol Synonym

Ph-p⁶⁰²

(Vasanthi et al., 2013)

ph-d⁶⁰²

ph-p⁶⁰²

(Vaziri et al., 2020, Dardalhon-Cuménal et al., 2018, Abed et al., 2013, Bengani et al., 2013, Gibert et al., 2011, Chen et al., 2008, DeVido et al., 2008)

ph⁶⁰²

(Wang et al., 2006, Boivin et al., 1999, Fauvarque et al., 1995)

Name Synonyms

Secondary FlyBase IDs

References (11)

Report Sections

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