FB2024_03 , released June 25, 2024
Allele: Dmel\lzr8
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General Information
Symbol
Dmel\lzr8
Species
D. melanogaster
Name
FlyBase ID
FBal0050122
Feature type
allele
Associated gene
Dmel\lz
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
Delta2-3 transposase
(Daga et al., 1996)
Progenitor genotype
lzSprite
(Daga et al., 1996)
Cytology
Description

Deletion of 11033bp covering part of the intron between exons VI and V, to some of the 3'UTR of the lz gene.

(Jackson Behan et al., 2005)

Deletion of sequences from the 3' part of the lz gene, leaving the first two introns intact.

(Flores et al., 1998)

Imprecise excision of the P-element of lzSprite.

(Daga et al., 1996)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
deletion
X:9,296,794..9,307,825 [+]
Comment:

Reported as a deletion of 11,033bp (GB:AF217651 coordinates 19,540–30,571).

(Jackson Behan et al., 2005)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Homozygotes have smooth eyes.

      (Flores et al., 1998)

      Adult eye has a smooth surface lacking lenses and the ommatidial array. Partial or complete loss of tarsal claws in the leg, a reduction of the third antennal segment and partial loss of female fertility.

      (Daga et al., 1996)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Complements

      lz77a7

      (Flores et al., 1998)
      Comments

      The smooth eye phenotype of lzr8 is fully complemented by lz77a7.

      (Flores et al., 1998)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      lzr8
      Name Synonyms
      Secondary FlyBase IDs
        References (3)