Deletes en transcription unit, approximate coordinates -12 to -14 of the inv-en region. The deletion removes the entire P{en-lacZ(Xho)} as well as 36 upstream base pairs and extends through the first exon and to within 3bp of the splice acceptor of the first intron. The homeodomain-encoding section of the gene is not deleted.
Fails to complement the adult phenotype of en1. Homozygous mutant embryos frequently hatch and show segment fusions varying from pair-wise fusions to milder fusions in which one or two denticle belts are partially fused.
Mutant embryos have some normal denticle belts, particularly in the anterior part of the embryo, but fused denticle belts with loss of naked cuticle are seen in approximately 50% of segments. The overall morphology of the central and peripheral nervous systems is slightly disrupted. The development of the NB 7-3 lineage is abnormal and only approximately 20% of the expected number of ventral ganglion serotonin-expressing neurons are seen in the mutant embryos.
Transheterozygotes with Df(3L)X37 and Df(3L)10H produce normal flies, transheterozygotes with Df(3L)E13 or Df(3R)slo8 produce flies with abnormal wings.
enC, ph-p410 has wing vein L4 phenotype
