FB2024_03 , released June 25, 2024
Allele: Dmel\Ras85D::Src64BV12.ΔCAAX.sev
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General Information
Symbol
Dmel\Ras85D::Src64BV12.ΔCAAX.sev
Species
D. melanogaster
Name
FlyBase ID
FBal0048922
Feature type
allele
Associated gene
Ras85D::Src64B
Associated Insertion(s)
Carried in Construct
P{sev-Src90-Ras1V12.ΔCAAX}
Key Links
Transgenic product class
Mutagen
Nature of the Allele
Transgenic product class
Mutagen
in vitro construct
(Therrien et al., 1995)
Progenitor genotype
Ras85DV12.ΔCAAX.sev
(Therrien et al., 1995)
Carried in construct
P{sev-Src90-Ras1V12.ΔCAAX}
Cytology
Description

Construct: First 90 amino acids of Src64B coding region (which includes a myristylation signal) has been fused in frame between the Ras85DV12.ΔCAAX.sev coding region and promoter.

(Therrien et al., 1995)
Allele components
Component
Use(s)
Regulatory region(s)
sev
Encoded product / tool
Ras85D::Src64B
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Rough eye phenotype similar to Ras85DV12.sev.

      (Karim et al., 1996)

      Same phenoytpe as Ras85DV12.sev : extra R7 cells and rough eyes.

      (Therrien et al., 1995)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Enhanced by
      Statement
      Reference

      Ras85D::Src64BV12.ΔCAAX.sev has phenotype, enhanceable by aopE-867

      (Karim et al., 1996)

      Ras85D::Src64BV12.ΔCAAX.sev has phenotype, enhanceable by aopyan-XE18

      (Karim et al., 1996)
      Suppressed by
      Statement
      Reference

      Ras85D::Src64BV12.ΔCAAX.sev has eye phenotype, suppressible by ksrS-638

      (Therrien et al., 1995)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Phenotype is suppressed by ksr mutants but not by βggt-I mutants.

      (Therrien et al., 1995)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      Comments
      Comments

      The 90 amino acids of Src64B target the gene product to the membrane.

      (Therrien et al., 1995)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      Ras85D::Src64BV12.ΔCAAX.sev
      Name Synonyms
      Secondary FlyBase IDs
        References (3)