FB2024_03 , released June 25, 2024
Allele: Dmel\Ras85DV12.ΔCAAX.sev
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General Information
Symbol
Dmel\Ras85DV12.ΔCAAX.sev
Species
D. melanogaster
Name
FlyBase ID
FBal0048927
Feature type
allele
Associated gene
Dmel\Ras85D
Associated Insertion(s)
Carried in Construct
P{sev-Ras1V12ΔCAAX}
Key Links
Transgenic product class
inframe_deletion
(Therrien et al., 1995)
missense_variant
(Therrien et al., 1995)
Mutagen
Nature of the Allele
Transgenic product class
inframe_deletion
(Therrien et al., 1995)
missense_variant
(Therrien et al., 1995)
Mutagen
in vitro construct
(Therrien et al., 1995)
Progenitor genotype
Ras85DV12.sev
(Therrien et al., 1995)
Carried in construct
P{sev-Ras1V12ΔCAAX}
Cytology
Description

Construct: Deletion of CAAX box.

(Therrien et al., 1995)
Allele components
Component
Use(s)
Regulatory region(s)
sev
Encoded product / tool
Ras85D
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      The addition of Ras85DV12.ΔCAAX.sev causes the transformation of cone cell precursors to supernumerary R7-like cells when expressed in cells of the R7 equivalence group (The R7 and cone cell precursors and the mystery cell).

      (Zhang and Lu, 2000)

      Wild type.

      (Therrien et al., 1995)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Suppressed by
      Statement
      Reference

      Ras85DV12.ΔCAAX.sev has photoreceptor cell R7 | ectopic phenotype, suppressible | partially by cnksag13L/sag[+]

      (Zhang and Lu, 2000)
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Ras85DV12.ΔCAAX.sev
      sev-RasV12.ΔCAAX
      (Zhang and Lu, 2000)
      Name Synonyms
      Secondary FlyBase IDs
        References (3)