FlyBase Allele Report: Dmel\Dsor1[S-1221]

General Information

Symbol

Dmel\Dsor1^S-1221

Species

D. melanogaster

Name

FlyBase ID

FBal0048254

Feature type

allele

Associated gene

Dmel\Dsor1

Associated Insertion(s)

Carried in Construct

Also Known As

Dsor1^S1221

Key Links

Allele class

Mutagen

ethyl methanesulfonate

Nature of the Allele

Allele class

Mutagen

ethyl methanesulfonate

(Karim et al., 1996)

Progenitor genotype

Cytology

Description

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 1 )

Disease

Interaction

References

ameliorates Huntington's disease

modeled by @Huntington's??not a valid allele symbol??@, @disease??not a valid allele symbol??@

(Miller et al., 2012)

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

lethal | recessive

(Karim et al., 1996)

Phenotype Manifest In

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressor of

Statement

Reference

Dsor1[+]/Dsor1^S-1221 is a suppressor of visible phenotype of Scer\GAL4^Tub.PU, csw^N308D.UASp

(Oishi et al., 2006)

Dsor1^S-1221 is a suppressor of increased cell number | third instar larval stage phenotype of hop^Tum

(Luo et al., 2002)

NOT Suppressor of

Statement

Reference

Dsor1[+], Ras85D[+], Ras85D^unspecified, Dsor1^S-1221 is a non-suppressor of decreased body size | pupal stage phenotype of Nf1^E2

(Walker et al., 2006)

Ras64B^unspecified, Dsor1[+], Ras64B[+], Dsor1^S-1221 is a non-suppressor of decreased body size | pupal stage phenotype of Nf1^E2

(Walker et al., 2006)

Dsor1^S-1221 is a non-suppressor of melanotic mass phenotype phenotype of hop^Tum

(Luo et al., 2002)

Dsor1^S-1221 is a non-suppressor of hyperplasia | third instar larval stage phenotype of hop^Tum

(Luo et al., 2002)

Phenotype Manifest In

Suppressor of

Statement

Reference

Dsor1[+]/Dsor1^S-1221 is a suppressor of wing vein | ectopic phenotype of Scer\GAL4^Tub.PU, csw^N308D.UASp

(Oishi et al., 2006)

Dsor1^S-1221 is a suppressor of lamellocyte | increased number phenotype of hop^Tum

(Luo et al., 2002)

Dsor1^S-1221 is a suppressor of hemocyte | increased number phenotype of hop^Tum

(Luo et al., 2002)

Dsor1^S-1221 is a suppressor of phenotype of Ras85D^V12.sev

(Karim et al., 1996)

NOT Suppressor of

Statement

Reference

Dsor1^S-1221 is a non-suppressor of embryonic/larval lymph gland phenotype of hop^Tum

(Luo et al., 2002)

Dsor1^S-1221 is a non-suppressor of melanotic mass phenotype of hop^Tum

(Luo et al., 2002)

Other

Statement

Reference

Dsor1[+]/Dsor1^S-1221, da² has follicle cell phenotype

(Smith et al., 2002)

Dsor1^S-1221, da² has follicle cell phenotype

(Smith et al., 2002)

Additional Comments

Genetic Interactions

Statement

Reference

Dsor1^S-1221 blocks differentiation of hop^Tum blood cells into lamellocytes and the increased accumulation of blood cells seen in hop^Tum larvae is strongly inhibited in the double mutant larvae. Double mutant lymph glands are overgrown and melanised.

(Luo et al., 2002)

No effect on the faf eye phenotype.

(Huang and Fischer-Vize, 1996)

Suppresses the rough eye phenotype of Ras85D^V12.sev. Enhances the phenotype of Ras85D^N17.sev. Suppresses the phenotype of phl::tor^13D.hs.sev. Suppresses the phenotype of Ras85D::Src64B^{V12.ΔCAAX.sev}. Enhances the aop^S2382 eye phenotype.

(Karim et al., 1996)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

Bloomington

8496

y¹ w^a Dsor1^S-1221/Basc

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

Dsor1^S-1221

(Miller et al., 2012, Oishi et al., 2006)

Dsor1^S1221

(Walker et al., 2006, Huang and Fischer-Vize, 1996)

Name Synonyms

Secondary FlyBase IDs

References (7)

Report Sections

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