FB2024_03 , released June 25, 2024
Allele: Dmel\Dhc64C1-1
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General Information
Symbol
Dmel\Dhc64C1-1
Species
D. melanogaster
Name
FlyBase ID
FBal0048181
Feature type
allele
Associated gene
Dmel\Dhc64C
Associated Insertion(s)
Carried in Construct
Key Links
Allele class

loss of function allele

Mutagen
Nature of the Allele
Allele class

loss of function allele

(Gepner et al., 1996)
Mutagen
ethyl methanesulfonate
(Gepner et al., 1996)
Progenitor genotype
Cytology
Description

Genomic Southern blotting revealed no polymorphism between the mutant and wild type chromosome.

(Gepner et al., 1996)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Lethality acts before or during larval stages. Low levels (3-12%) of embryonic lethality are observed.

      (Gepner et al., 1996)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Enhancer of
      Statement
      Reference

      Dhc64C[+]/Dhc64C1-1 is an enhancer of visible | dominant phenotype of S1

      (Iyadurai et al., 2008)

      Dhc64C1-1 is an enhancer of visible | dominant phenotype of EgfrE1

      (Iyadurai et al., 2008)

      Dhc64C[+]/Dhc64C1-1 is an enhancer of visible | dominant phenotype of DCTN1-p150Gl-1, S[+]/S1

      (Iyadurai et al., 2008)
      Phenotype Manifest In
      Enhancer of
      Statement
      Reference

      Dhc64C[+]/Dhc64C1-1 is an enhancer of eye phenotype of S1

      (Iyadurai et al., 2008)

      Dhc64C1-1 is an enhancer of eye phenotype of EgfrE1

      (Iyadurai et al., 2008)

      Dhc64C[+]/Dhc64C1-1 is an enhancer of eye phenotype of DCTN1-p150Gl-1, S[+]/S1

      (Iyadurai et al., 2008)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Dhc64C1-1/+ enhances the rough eye phenotype of S1/+ flies, resulting in more disruption of the hexagonal packing of the ommatidia. and in a smaller eye.

      (Iyadurai et al., 2008)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      Comments
      Comments

      Fails to complement Dhc64C8-1.

      (Gepner et al., 1996)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      Dhc64C1-1
      Dhc1-1
      (Iyadurai et al., 2008)
      l(3)64Ca1-1
      Name Synonyms
      Secondary FlyBase IDs
        References (2)