FlyBase Allele Report: Dmel\stg[unspecified]

General Information

Symbol

Dmel\stg^unspecified

Species

D. melanogaster

Name

FlyBase ID

FBal0046527

Feature type

allele

Associated gene

Dmel\stg

Associated Insertion(s)

Carried in Construct

Key Links

Allele class

Mutagen

Nature of the Allele

Allele class

Mutagen

Progenitor genotype

Cytology

Description

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

lethal - all die during embryonic stage | recessive

(Tearle and Nusslein-Volhard, 1987)

some die during embryonic stage | recessive

(Tearle and Nusslein-Volhard, 1987)

Phenotype Manifest In

mitotic cell cycle | embryonic stage

(Tearle and Nusslein-Volhard, 1987)

neuropil | embryonic stage

(Tearle and Nusslein-Volhard, 1987)

tormogen cell

(Hartenstein and Posakony, 1990)

ventral denticle belt

(Tearle and Nusslein-Volhard, 1987)

Detailed Description

Statement

Reference

Homozygous embryos develop sensory neurons at the dorsal and lateral levels only. Hair shafts and sockets of various types of sensilla do not form. There are no concentric cellular sheaths around the dendrites.

(Hartenstein and Posakony, 1990)

stg^unspecified mutant embryos have reduced denticle bands. There is a failure of post-blastoderm mitoses with fewer and larger cells in all tissues. The neuropile is absent.

(Tearle and Nusslein-Volhard, 1987)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhancer of

Statement

Reference

stg^unspecified/stg[+] is an enhancer of visible phenotype of Scer\GAL4^Bx-MS1096, trbl^UAS.cGa

(Gawlinski et al., 2007)

stg^unspecified/stg[+] is an enhancer of visible phenotype of CycE^JP

(Brumby et al., 2004)

stg^unspecified/stg[+] is an enhancer of visible phenotype of Myt1^GMR.PP

(Price et al., 2002)

NOT Enhancer of

Statement

Reference

stg^unspecified/stg[+] is a non-enhancer of visible phenotype of Scer\GAL4^Bx-MS1096, Z600^UAS.cGa

(Gawlinski et al., 2007)

stg^unspecified/stg[+] is a non-enhancer of visible phenotype of Wee1^GMR.PP

(Price et al., 2002)

NOT Suppressor of

Statement

Reference

stg^unspecified/stg[+] is a non-suppressor of visible phenotype of Scer\GAL4^Bx-MS1096, Z600^UAS.cGa

(Gawlinski et al., 2007)

Phenotype Manifest In

Enhancer of

Statement

Reference

stg^unspecified/stg[+] is an enhancer of wing phenotype of Scer\GAL4^Bx-MS1096, trbl^UAS.cGa

(Gawlinski et al., 2007)

stg^unspecified/stg[+] is an enhancer of eye phenotype of CycE^JP

(Brumby et al., 2004)

stg^unspecified/stg[+] is an enhancer of eye phenotype of Myt1^GMR.PP

(Price et al., 2002)

NOT Enhancer of

Statement

Reference

stg^unspecified/stg[+] is a non-enhancer of wing phenotype of Scer\GAL4^Bx-MS1096, Z600^UAS.cGa

(Gawlinski et al., 2007)

stg^unspecified/stg[+] is a non-enhancer of eye phenotype of Wee1^GMR.PP

(Price et al., 2002)

stg^unspecified is a non-enhancer of embryonic epidermis phenotype of Scer\GAL4^da.G32, crb^{intra.UAS.Tag:MYC}

(Klebes and Knust, 2000)

Suppressor of

Statement

Reference

stg^unspecified/stg[+] is a suppressor of nucleus | embryonic stage phenotype of lok^E51

(Xu and Du, 2003)

stg^unspecified is a suppressor of phenotype of trbl^EP1119

(Mata et al., 2000)

NOT Suppressor of

Statement

Reference

stg^unspecified/stg[+] is a non-suppressor of wing phenotype of Scer\GAL4^Bx-MS1096, Z600^UAS.cGa

(Gawlinski et al., 2007)

stg^unspecified is a non-suppressor of embryonic epidermis phenotype of Scer\GAL4^da.G32, crb^{intra.UAS.Tag:MYC}

(Klebes and Knust, 2000)

Other

Statement

Reference

Myt1^GMR.PP, stg^unspecified/stg[+] has interommatidial bristle phenotype

(Price et al., 2002)

Myt1^GMR.PP, stg^unspecified has interommatidial bristle phenotype

(Price et al., 2002)

Additional Comments

Genetic Interactions

Statement

Reference

The fraction of embryos derived from lok^E51 females which have abnormal nuclei is reduced (from 61.5 +/- 1.1%) if the females also carry one copy of stg^unspecified (to 38.5 +/- 7.0% of embryos).

(Xu and Du, 2003)

Myt1^GMR.PP stg^unspecified/+ eyes lack bristles.

(Price et al., 2002)

In double mutant stg^unspecified trbl^unspecified or stg^unspecified Df(3L)XG10 embryos no mitosis takes place during gastrulation and the ventral furrow forms as in wild-type.

(Großhans and Wieschaus, 2000)

Addition of stg^unspecified has no effect on the multicellular epithelium phenotype seen in crb^{intra.Scer\UAS.T:Hsap\MYC} embryos when driven by Scer\GAL4^da.G32.

(Klebes and Knust, 2000)

Embryos doubly mutant for trbl and stg do not show the trbl mutant phenotype.

(Mata et al., 2000)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Partially rescued by

stg^unspecified is partially rescued by stg^BCDE

(Edgar et al., 1994)

stg^unspecified is partially rescued by stg^CD

(Edgar et al., 1994)

stg^unspecified is partially rescued by stg^BCD

(Edgar et al., 1994)

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (3)

Reported As

Symbol Synonym

Cdc25^string

(Vidwans et al., 2002)

stg^unspecified

unspecified

(Hartenstein and Posakony, 1990)

Name Synonyms

Secondary FlyBase IDs

References (15)

Report Sections

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