FB2024_03 , released June 25, 2024
Allele: Dmel\groBFP2
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General Information
Symbol
Dmel\groBFP2
Species
D. melanogaster
Name
FlyBase ID
FBal0045820
Feature type
allele
Associated gene
Dmel\gro
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
ethyl methanesulfonate
(Fischer-Vize et al., 1992)
Progenitor genotype
Cytology
Description
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      No effect on the faf eye phenotype.

      (Huang and Fischer-Vize, 1996)

      Mutation has no effect on rhohs.sev rough eye phenotype.

      (Freeman, 1994)

      Flies are only marginally fertile, and their wings are broader and slightly held out. The eyes are slightly bulged and have some bristle spacing defects. Approximately two-thirds of the ommatidia have one, two or three additional outer photoreceptor cells, and the orientation of the ommatidia is irregular. groBFP2/gro1 transheterozygotes have wild-type eyes. In mosaic animals, approximately 17% of ommatidia containing both wild-type and groBFP2 cells are "rescued" to wild-type. Phenotypically mutant ommatidia in which the cells are genotypically wild-type are also seen at the edge of mutant clones.

      (Fischer-Vize et al., 1992)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Other
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Heterozygotes for E(spl) that are also heterozygous for groBFP2 have eye defects that are similar but not identical to groBFP2 homozygotes.

      (Fischer-Vize et al., 1992)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescued by

      groBFP2 is rescued by gro+t10.4

      (Fischer-Vize et al., 1992)
      Comments

      E(spl)+t10.4 rescues the homozygous groBFP2 phenotype.

      (Fischer-Vize et al., 1992)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      Comments
      Comments

      groBFP2 has been characterised.

      (Fischer-Vize et al., 1992)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      groBFP2
      groFP2
      (Freeman, 1994)
      Name Synonyms
      Secondary FlyBase IDs
        References (4)