FlyBase Allele Report: Dmel\w[+tAR]

General Information

Symbol

Dmel\w^+tAR

Species

D. melanogaster

Name

FlyBase ID

FBal0040116

Feature type

allele

Associated gene

Dmel\w

Associated Insertion(s)

Carried in Construct

P{wA^R}

Key Links

Transgenic product class

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

Mutagen

in vitro construct

(Hazelrigg et al., 1984)

Progenitor genotype

w^+t11.7

(Hazelrigg et al., 1984)

Carried in construct

P{wA^R}

Cytology

Description

Construct: Insertion of 11.7kb fragment carrying the w gene from coordinates -5.1 to +6.6, with an alteration beyond the 3' end of the transcribed region, into the P-element of pV10.

(Hazelrigg et al., 1984)

Allele components

Component

Use(s)

Encoded product / tool

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

wild-type

(Hazelrigg et al., 1984)

Phenotype Manifest In

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Expression of w^+tAR in the anterior portion of the eye of w^e(g)/Y, g² mutant flies results in normal pigmentation of this region.

(Lloyd et al., 2002)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Partially rescues

w^+tAR partially rescues w¹

(Lloyd et al., 2002)

Comments

Transfection of w^+tAR into w¹ mutant flies increases pigment levels in the eye from <1% to 64%.

(Lloyd et al., 2002)

Images (0)

Mutant

Wild-type

Stocks (11)

Bloomington

10797

w¹¹¹⁸; P{wA^R}4-24

3125

Df(3L)fz-GS1a, P{wA^R}66E/TM3, Sb¹

3124

Df(3L)fz-GF3b, P{wA^R}66E/TM6B, Tb⁺

10919

w¹¹¹⁸; P{wA^R}rk^11P, l(2)*^*/CyO

7246

w^*; P{wA^R}jar²⁰⁹⁵/TM3, Sb¹ Ser¹

7247

w^*; P{wA^R}jar¹⁶⁴⁶/TM3, Sb¹ Ser¹

1296

C(1)M3, y¹/Dp(1;Y)y⁺; P{wA^R}tsh^4-3; awd^K

Kyoto

106864

Df(3L)fz-GS1a, P{wA^R}66E/TM3, Sb¹

106863

Df(3L)fz-GF3b, P{wA^R}66E/TM6B, Tb¹ ca¹

106268

C(1)M3, y¹/Dp(1;Y)y⁺; P{wA^R}tsh^4-3; awd^K

111267

y^d2 w¹¹¹⁸ P{ey-FLP.N}2 P{5xglBS-lacZ.38-1}TPN1; P{wA^R}rk^11P P{neoFRT}40A/CyO y⁺

Notes on Origin

Discoverer

Comments

Variegated eye phenotype can be observed in lines where the insert is near heterochromatin.

(Levis et al., 1985)

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

w^+tAR

Name Synonyms

Secondary FlyBase IDs

References (8)

Report Sections

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