FB2024_03 , released June 25, 2024
Allele: Dmel\sggMA27
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General Information
Symbol
Dmel\sggMA27
Species
D. melanogaster
Name
FlyBase ID
FBal0035600
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Nature of the Allele
Allele class
Progenitor genotype
Cytology
Description
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DNA sequence
Protein sequence
 
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Hemizygous progeny derived from heterozygous females die during early larval stages. All embryos derived from homozygous germline clones die during embryonic development, and have very poorly differentiated cuticle which sometimes has holes in it. The head is defective, with abnormal spiracles, and the filzkorper material is very prominent. The CNS is very disorganised and the brain often protrudes dorsally rather than being covered by epidermis. The PNS is abnormal. Some embryos have a less extreme phenotype, with more cuticle differentiation and some defective denticle belt differentiation. The phenotype can be partially rescued by a paternal copy of wild-type sgg. Homozygous clones in the wing show homeotic transformation of hairs into bristles.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments

sggmR10 rescues hemizygous males to pharate adults.

Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (3)
Reported As
Symbol Synonym
Name Synonyms
Secondary FlyBase IDs
    References (3)