FB2024_03 , released June 25, 2024
Allele: Dmel\msl-1γ216
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General Information
Symbol
Dmel\msl-1γ216
Species
D. melanogaster
Name
FlyBase ID
FBal0035232
Feature type
allele
Associated gene
Dmel\msl-1
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
gamma ray
(Palmer et al., 1993)
Progenitor genotype
Cytology
Description

Deletion of 2.3kb detected by Southern blot at coordinate +75kb of the genomic DNA walk.

(Palmer et al., 1993)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Other
      Statement
      Reference

      Df(3L)Rac1/+, msl-1γ216 has lethal | dominant phenotype

      (Furuhashi et al., 2006)
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      msl-1γ216/+ ; Df(3L)Rac1/+ double heterozygous males show a significant reduction in male viability compared to either single mutant.

      (Furuhashi et al., 2006)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Fails to complement

      msl-1kmB

      (Bevan et al., 1993)
      Comments

      msl-1kmB/msl-1γ216 males do not survive, dying as larvae.

      (Bevan et al., 1993)
      Images (0)
      Mutant
      Wild-type
      Stocks (2)
      Notes on Origin
      Discoverer
      Comments
      Comments

      H4Ac16, acetylated form of His4, is not localised to the X chromosome in male salivary gland nuclei of msl-1γ216/msl-1γ269 heterozygotes.

      (Bone et al., 1994)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      msl-1216
      (Bevan et al., 1993)
      msl-1γ216
      (Leatham-Jensen et al., 2019, Furuhashi et al., 2006)
      msl1γ216
      (McCarthy et al., 2022)
      Name Synonyms
      Secondary FlyBase IDs
        References (10)