FB2024_03 , released June 25, 2024
Allele: Dmel\chifA507
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General Information
Symbol
Dmel\chifA507
Species
D. melanogaster
Name
FlyBase ID
FBal0034347
Feature type
allele
Associated gene
Dmel\chif
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
P-element activity
(Roote, 1995.5.4)
Progenitor genotype
Cytology
Description
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      chifEY05746/chifA507 mutant flies show significant indirect flight muscle degeneration compared to controls.

      chifBG02820a/chifA507 mutant flies show significant indirect flight muscle degeneration compared to controls.

      (Kucherenko et al., 2011)

      Shows chif mutant phenotype.

      (Roote, 1996.9.24)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      NOT Enhancer of
      Statement
      Reference

      chifA507/chif[+] is a non-enhancer of indirect flight muscle cell phenotype of DgRNAi.UAS, Scer\GAL4Act.PU

      (Kucherenko et al., 2011)
      Other
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      chif Dys double heterozygous flies (chifA507/Df(3R)Exel6184) exhibit indirect flight muscle degeneration.

      One copy of chifA507 does not enhance the indirect flight muscle degeneration seen when DgdsRNA.Scer\UAS is expressed under the control of Scer\GAL4tub.PU.

      (Kucherenko et al., 2011)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (2)
      Notes on Origin
      Discoverer

      C. Wilson.

      (Roote, 1995.5.4)

      The chifA507 allele may be independent of the P{lArB}A507.2M2 insertion it is associated with.

      (Ashburner et al., 1999)

      Induced on: CyO, P{lArB}A507.2M2.

      (Roote, 1996.9.24)
      Comments
      Comments

      Arose on a CyO chromosome which also carries P{lArB}A507.2M2. Phenotypic data included in FBrf0051973.

      (Roote, 1995.5.4)

      P{lArB}A507.2M2 is apparently unrelated to the chif mutant phenotype.

      (Roote, 1996.9.24)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      chifA507
      (Kucherenko et al., 2011)
      Name Synonyms
      Secondary FlyBase IDs
        References (5)