FB2024_03 , released June 25, 2024
Allele: Dmel\Polr2I+t5.3
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General Information
Symbol
Dmel\Polr2I+t5.3
Species
D. melanogaster
Name
FlyBase ID
FBal0033989
Feature type
allele
Associated gene
Dmel\Polr2I
Associated Insertion(s)
Carried in Construct
P{CaSX/K5.3}
Key Links
Genomic Maps

Transgenic product class
Mutagen
Nature of the Allele
Transgenic product class
Mutagen
in vitro construct
(Smith and Corces, 1995, Harrison et al., 1992)
Progenitor genotype
Carried in construct
P{CaSX/K5.3}
Cytology
Description

5.3kb XbaI KpnI fragment of RpII15 lacking the complete coding region but including 4kb of sequence distal to su(Hw).

(Harrison et al., 1992)
Allele components
Component
Use(s)
Regulatory region(s)
Polr2I
Encoded product / tool
Polr2I
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
rescue_region
3R:14,307,237..14,312,195 [+]
Linked to:
XbaI-KpnI restriction fragment
Comment:

Position of restriction fragment on reference sequence inferred by FlyBase curator.

(Harrison et al., 1992)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      su(Hw)V P{CaSX/K5.3} combination is viable as the lethality associated with Df(3R)su(Hw)V (due to deletion of RpII15) has been rescued by transformation with a 5.3kb genomic fragment of RpII15.

      (Smith and Corces, 1995)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      Polr2I+t5.3 rescues Polr2IV

      (Harrison et al., 1992)
      Comments

      Rescues the lethality of Df(3R)su(Hw)V.

      (Harrison et al., 1992)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Polr2I+t5.3
      RpII15+t5.3
      Name Synonyms
      Secondary FlyBase IDs
        References (2)