FB2024_03 , released June 25, 2024
Allele: Dmel\wE.BR
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General Information
Symbol
Dmel\wE.BR
Species
D. melanogaster
Name
FlyBase ID
FBal0033135
Feature type
allele
Associated gene
Dmel\w
Associated Insertion(s)
Carried in Construct
P{su(Hw)BR-w.2}
Key Links
Transgenic product class
Mutagen
Nature of the Allele
Transgenic product class
Mutagen
in vitro construct
(Roseman et al., 1993)
Progenitor genotype
w+mET
(Roseman et al., 1993)
Carried in construct
P{su(Hw)BR-w.2}
Cytology
Description

Construct: w+mC minigene altered to include the w eye enhancer (nucleotides -1084 to -1465 of Qian et al., Genetics 131:79-90 ), upstream of a su(Hw) binding region (all 12 binding sites, nucleotides 647 to 1077 of Marlor et al., Mol Cell Biol 6:1129-1134 ), upstream of the w coding region.

(Roseman et al., 1993)
Allele components
Component
Use(s)
Encoded product / tool
w
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Eye colour: flies carrying wE.BR have brown eyes.

      (Soldatov et al., 1999)

      Range of phenotypes from yellow to brown.

      (Roseman et al., 1993)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Enhanced by
      Statement
      Reference

      wE.BR, zv77h has abnormal eye color phenotype, enhanceable by Taf91

      (Soldatov et al., 1999)
      Other
      Statement
      Reference

      wE.BR, zv77h has abnormal eye color phenotype

      (Soldatov et al., 1999)
      Phenotype Manifest In
      Enhanced by
      Statement
      Reference

      wE.BR, zv77h has pigment cell phenotype, enhanceable by Taf91

      (Soldatov et al., 1999)
      Other
      Statement
      Reference

      wE.BR, zv77h has pigment cell phenotype

      (Soldatov et al., 1999)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      The eye pigmentation is reduced if flies carrying wE.BR are also carrying e(y)11 and zv77h.

      (Soldatov et al., 1999)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      wE.BR
      Name Synonyms
      Secondary FlyBase IDs
        References (2)