FlyBase Allele Report: Dmel\neur[KX9]

General Information

Symbol

Dmel\neur^KX9

Species

D. melanogaster

Name

FlyBase ID

FBal0032228

Feature type

allele

Associated gene

Dmel\neur

Associated Insertion(s)

Carried in Construct

Also Known As

neu^KX9

Key Links

Allele class

amorphic allele - genetic evidence

Mutagen

Nature of the Allele

Allele class

amorphic allele - genetic evidence

(Brand et al., 1993)

Mutagen

Progenitor genotype

Cytology

Description

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal memory

(Pavlopoulos et al., 2008)

increased cell number | embryonic stage

(Bodmer et al., 1993)

Phenotype Manifest In

ectoderm

(Bodmer et al., 1993)

embryonic epidermis

(Doherty et al., 1997)

external sensory organ precursor cell | ectopic

(Bodmer et al., 1993)

female germline stem cell | germline clone

(Ward et al., 2006)

Detailed Description

Statement

Reference

neur^KX9 heterozygotes exhibit learning and 9-minute memory abilities that appear identical to wild-type controls. However, these animals display significantly reduced 260-minute memory.

(Pavlopoulos et al., 2008)

neur^KX9 mutant germline stem cells differentiate and leave the niche, resulting in an empty germarium phenotype when both germline stem cells are mutant.

(Ward et al., 2006)

Hyperplasia of replicating sensory precursors: due to an increased number of ectodermal cells being recruited as sensory precursor cells.

(Bodmer et al., 1993)

Increase in SMCs per cluster in embryos lacking the maternal product.

(Goriely et al., 1991)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

NOT suppressed by

Statement

Reference

neur^KX9 has embryonic epidermis phenotype, non-suppressible by bib^UAS.cDa/Scer\GAL4^h-1J3

(Doherty et al., 1997)

Additional Comments

Genetic Interactions

Statement

Reference

The cuticle defect of homozygous embryos is not rescued by bib^Scer\UAS.cDa expressed under the control of Scer\GAL4^h-1J3.

(Doherty et al., 1997)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (3)

Reported As

Symbol Synonym

neu^KX9

(Doherty et al., 1997, Bodmer et al., 1993)

neur^KX9

(Pavlopoulos et al., 2008, Ward et al., 2006)

neur^Kx9

(Rhyu et al., 1994)

Name Synonyms

Secondary FlyBase IDs

References (8)

Report Sections

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