FB2024_03 , released June 25, 2024
Allele: Dmel\Ubxbx-83Kb
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General Information
Symbol
Dmel\Ubxbx-83Kb
Species
D. melanogaster
Name
FlyBase ID
FBal0030347
Feature type
allele
Associated gene
Dmel\Ubx
Associated Insertion(s)
gypsy{}Ubxbx-83Kb
Carried in Construct
Also Known As
bx83Kb
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
spontaneous
(Peifer and Bender, 1986)
Progenitor genotype
Associated Insertion(s)
gypsy{}Ubxbx-83Kb
Cytology

Polytene chromosomes normal.

(Castelli-Gair and Garcia-Bellido, 1990)
Description

Mutation in downstream control region.

(Irvine et al., 1993)

gypsy element insertion into the bx regulatory region. The direction of transcription of the gypsy element is in the opposite direction to Ubx transcription.

(Castelli-Gair and Garcia-Bellido, 1990)

Insertion of gypsy element, with its direction of transcription in the opposite orientation to the direction of Ubx transcription, into an intron of the Ubx transcription unit.

(Little et al., 1990)

Insertion of a gypsy element. The gypsy element is transcribed in the same direction as Ubx.

(Micol et al., 1990)

gypsy insertion at -55kb in the same orientation as Ubx direction of transcription.

(Peifer and Bender, 1986)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Does not affect the frequency of the trx bithorax-variegated phenotype in heterozygous combination with Df(3R)red-P52.

      (Castelli-Gair and Garcia-Bellido, 1990)

      Haltere are transformed to wing and are 20-25% of wing size, dorsal tissue of T3 is incompletely transformed to metanotum, hypopleural plates are incompletely transformed to sternopleural plates, 9-10 hypopleural bristles are still present and the anterior third leg displays a strong transformation to anterior second leg, as seen by the bristle pattern. Phenotype can be suppressed by su(Hw) mutations.

      (Peifer and Bender, 1986)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Enhancer of
      Statement
      Reference

      Ubx[+]/Ubxbx-83Kb is an enhancer of visible | homeotic phenotype of Dsp11

      (Decoville et al., 2001)
      Phenotype Manifest In
      Enhancer of
      Statement
      Reference

      Ubx[+]/Ubxbx-83Kb is an enhancer of haltere phenotype of Dsp11

      (Decoville et al., 2001)

      Ubx[+]/Ubxbx-83Kb is an enhancer of wing | ectopic phenotype of Dsp11

      (Decoville et al., 2001)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      The frequency of transformation of halteres into wings seen in Dsp11/Y flies is enhanced by Ubxbx-83Kb/+. The enhancement is dramatically reduced if the female parents are heterozygous rather than homozygous for Dsp11.

      (Decoville et al., 2001)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer

      Kuhn.

      (Peifer and Bender, 1986)

      Kuhn, 1983.

      (Lindsley and Zimm, 1992)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (8)
      References (9)