FB2024_03 , released June 25, 2024
Allele: Dmel\Su(var)205hs.PE
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General Information
Symbol
Dmel\Su(var)205hs.PE
Species
D. melanogaster
Name
heat shock constuct of Eissenberg
FlyBase ID
FBal0030285
Feature type
allele
Associated gene
Dmel\Su(var)205
Associated Insertion(s)
Carried in Construct
P{neoRHSHP1}
Also Known As
P{neoR}HSHP1.83C, hs-HP1a
Key Links
Transgenic product class
cDNA
(Eissenberg et al., 1992)
wild_type
(Eissenberg et al., 1992)
Mutagen
Nature of the Allele
Transgenic product class
cDNA
(Eissenberg et al., 1992)
wild_type
(Eissenberg et al., 1992)
Mutagen
in vitro construct
(Eissenberg and Hartnett, 1993, Eissenberg et al., 1992)
Progenitor genotype
Carried in construct
P{neoRHSHP1}
Cytology
Description

Minimal Hsp70 promoter drives the expression of Su(var)205 cDNA containing 63 nucleotides of 5' non-coding sequence and the entire open reading frame and 3' non-coding sequence.

(Eissenberg et al., 1992)
Allele components
Component
Use(s)
Regulatory region(s)
Hsp70
Encoded product / tool
Su(var)205
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      The frequency of heterochromatization of regions subject to PEV in the T(1;2)dorvar7 rearrangement is not affected by expression of Su(var)205hs.PE under the control of heat shock.

      (Belyaeva et al., 2003)

      Heat shock strongly enhances transinactivation of bw caused by Tp(2;2)bw-DX7.

      (Sass and Henikoff, 1999)

      Variegation of the w gene in the rearrangement In(1)wm4h is enhanced by expression of the heat shock activated Su(var)205 construct.

      (Eissenberg and Hartnett, 1993, Eissenberg et al., 1992)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      Su(var)205hs.PE rescues Su(var)2051

      (Kellum and Alberts, 1995)

      Su(var)205hs.PE rescues Su(var)2052

      (Kellum and Alberts, 1995)

      Su(var)205hs.PE rescues Su(var)2054

      (Kellum and Alberts, 1995)

      Su(var)205hs.PE rescues Su(var)2055

      (Kellum and Alberts, 1995)
      Partially rescues

      Su(var)205hs.PE partially rescues Su(var)2055/Su(var)2054

      (Fanti et al., 1998)
      Comments

      The abnormal metaphase configurations seen in the brains of Su(var)2054/Su(var)2055 larvae are partly rescued by expression of Su(var)205hs.PE, although a high frequency of chromosome aberrations are seen.

      (Fanti et al., 1998)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Su(var)205hs.PE
      Name Synonyms
      heat shock constuct of Eissenberg
      Secondary FlyBase IDs
        References (11)