FB2024_03 , released June 25, 2024
Allele: Dmel\Abd-BFab7-3
Open Close
General Information
Symbol
Dmel\Abd-BFab7-3
Species
D. melanogaster
Name
FlyBase ID
FBal0028658
Feature type
allele
Associated gene
Dmel\Abd-B
Associated Insertion(s)
Carried in Construct
Also Known As
Fab-73, Fab73
Key Links
Allele class

gain of function allele

Mutagen
Nature of the Allele
Allele class

gain of function allele

(Galloni et al., 1993)
Mutagen
Delta2-3 transposase
(Galloni et al., 1993)
Progenitor genotype
Abd-Bblt
(Hagstrom et al., 1996, Galloni et al., 1993)
Cytology
Description

Deletion of DNA.

(Mihaly et al., 1997)

Imprecise excision of the P{bluetail} insertion deleting the major hypersensitive sites HS1 and HS2 but leaving HS3.

(Hagstrom et al., 1996)

Deletion within the Fab-7 element.

(Zhou et al., 1996)

Deletion with a lesion in the Fab7 domain.

(Karch et al., 1994)

Deletion of all but the distal terminal repeat of the transposon insertion, along with 2.5-3.0kb of DNA immediately proximal to the insertion site, including two of the three nuclease hypersensitive regions.

(Galloni et al., 1993)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Incomplete transformation of PS11 to PS12.

      (Hagstrom et al., 1997)

      Transforms parasegment 11 to parasegment 12 identity.

      (Hagstrom et al., 1996)

      Transformation of abdominal segment 6 to A7 identity. Clones within parasegment 11 are not transformed.

      (Karch et al., 1994)

      A6 is completely transformed into A7 in homozygotes.

      (Galloni et al., 1993)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Enhanced by
      Statement
      Reference

      Abd-BFab7-3 has phenotype, enhanceable by Pc3

      (Mihaly et al., 1997)

      Abd-BFab7-3 has phenotype, enhanceable by ScmD1

      (Mihaly et al., 1997)

      Abd-BFab7-3 has phenotype, enhanceable by Df(2R)trix

      (Mihaly et al., 1997)

      Abd-BFab7-3 has phenotype, enhanceable by Pcl10

      (Mihaly et al., 1997)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Transformation of abdominal segment A6 to A7 in homozygous flies is enhanced by Polycomb group mutations such as Pc3, Pcl10, ScmD1 and Df(2R)trix.

      (Mihaly et al., 1997)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      Comments
      Comments

      Expressivity less than 100%: small untransformed regions are observed that appear to be clonal in origin.

      (Galloni et al., 1993)

      Deletion removes major nuclear hypersensitive sites I and II and all of the minor sites on the proximal side.

      (Karch et al., 1994)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      Abd-BFab7-3
      Fab-73
      (Brown et al., 2003, Mihaly et al., 1997, Hagstrom et al., 1996, Zhou et al., 1996, Galloni et al., 1993)
      Fab73
      (Hagstrom et al., 1997, Karch et al., 1994)
      Name Synonyms
      Secondary FlyBase IDs
        References (7)