FlyBase Allele Report: Dmel\Abd-B[S10]

General Information

Symbol

Dmel\Abd-B^S10

Species

D. melanogaster

Name

FlyBase ID

FBal0027954

Feature type

allele

Associated gene

Dmel\Abd-B

Associated Insertion(s)

Carried in Construct

Also Known As

iab7^S10

Key Links

Allele class

Mutagen

gamma ray

Nature of the Allele

Allele class

Mutagen

gamma ray

(Kuhn et al., 1993, Tiong et al., 1988)

Progenitor genotype

Caused by aberration

Tp(3;Y)Abd-B^S10

Cytology

Description

Molecular lesion lies at 154-158kb.

(Hendrickson and Sakonju, 1995)

Breakpoint maps to coordinate +148kb.

(Kuhn et al., 1993)

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

visible | homeotic

(Tiong et al., 1988)

Phenotype Manifest In

abdominal segment 5

(Hendrickson and Sakonju, 1995)

abdominal segment 6

(Hendrickson and Sakonju, 1995)

abdominal segment 7

(Hendrickson and Sakonju, 1995)

adult abdominal segment 5

(Tiong et al., 1988)

adult abdominal segment 6

(Tiong et al., 1988)

adult abdominal segment 7

(Tiong et al., 1988)

Detailed Description

Statement

Reference

Hemizygotes show an iab5,6,7 mutant phenotype: abdominal segments A5-A7 transform towards A4. Heterozygotes with Abd-B point or pseudopoint mutations cause a less severe mutant phenotype, with mixed A5/A6 identity in A6 and A7.

(Hendrickson and Sakonju, 1995)

Hemizygous males show an extreme transformation of A5, A6 and A7; pigmentation is patchy but trichome density is high and typical of abdominal tergite 4.

(Tiong et al., 1988)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Other

Statement

Reference

Abd-B^S10, Ubx^MX12 has abdominal segment 7 phenotype

(Hendrickson and Sakonju, 1995)

Abd-B^S10, Ubx^MX12 has abdominal segment 5 phenotype

(Hendrickson and Sakonju, 1995)

Abd-B^S10, Ubx^MX12 has abdominal segment 6 phenotype

(Hendrickson and Sakonju, 1995)

Abd-B^S10, abd-A^M1 has abdominal segment 7 phenotype

(Hendrickson and Sakonju, 1995)

Abd-B^S10, abd-A^M1 has abdominal segment 5 phenotype

(Hendrickson and Sakonju, 1995)

Abd-B^S10, abd-A^M1 has abdominal segment 6 phenotype

(Hendrickson and Sakonju, 1995)

Additional Comments

Genetic Interactions

Statement

Reference

Phenotype over Ubx^MX12, abd-A^M1, Abd-B^M8 is the same as when over Abd-B^-.

(Hendrickson and Sakonju, 1995)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

Comments

No effect on penetrance of head defect phenotype when in trans with Abd-B^iab9-tuh-3.

(Kuhn et al., 1993)

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (5)

Reported As

Symbol Synonym

Abd-B^S10

(Singh and Mishra, 2015)

Df-S10

(Kuhn et al., 1993)

S10

(Ronshaugen and Levine, 2004)

iab-8^S10

(Duncan, 2002)

iab7^S10

(Hendrickson and Sakonju, 1995, Hopmann et al., 1995)

Name Synonyms

Secondary FlyBase IDs

References (7)

Report Sections

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