Heterozygotes show an increase in crossing over between kni and pp. Heterozygotes show an increase in crossing over between se and kni, between kni and ss and between ss and e. Heterozygotes show an increase in crossing over between y and N. Heterozygous females show reduced disjunction and/or chromosome loss in oogenesis compared to controls.
Moderate maternal effects as seen by elevated w+ eye pigment levels in non-suppressor bearing offspring of Su(var)2-1 females. Removal of segments of heterochromatin from the genome by loss of the Y chromosome abolishes the suppression of the position effect variegation phenotype. The extent of hemizygous lethality is dramatically enhanced in the presence of extra heterochromatin ( attachedXX/Y females) whereas the lethality did not occur in the absence of the Y (X/O males). The effect of the Su(var)2-1207 allele is unchanged in heterozygotes with Df(2R)M41A10 (which lacks 2R heterochromatin). Viability of the Su(var)2-1207 heterozygotes is butyrate-sensitive.
Moderate enhancer of variegation at the lt locus.
Su(var)2-1207; Dp(2;2)Mdh3 double mutants display reductions in eye pigmentation.
homozygous lethal
Originally isolated as a dominant suppressor of the w+ gene on In(1)wm4.