FB2024_03 , released June 25, 2024
Allele: Dmel\run28
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General Information
Symbol
Dmel\run28
Species
D. melanogaster
Name
FlyBase ID
FBal0014873
Feature type
allele
Associated gene
Dmel\run
Associated Insertion(s)
Carried in Construct
Also Known As
runYE96, runtYE96
Key Links
Allele class

hypomorphic allele - genetic evidence

Mutagen
Nature of the Allele
Allele class

hypomorphic allele - genetic evidence

(Torres and Sanchez, 1992)
Mutagen
ethyl methanesulfonate
Progenitor genotype
Cytology
Description
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      run16/shakB-, run21/shakB- and run28/shakB- heterozygotes are fully viable and exhibit no neuronal defects.

      (Baird et al., 1990)

      Strong allele.

      (DiNardo and O'Farrell, 1987)

      Mirror-image duplication of abdominal denticle bands 2, 4, 6 and 8, deletion of odd numbered abdominal bands, dominant defects in T3, A1 and A6.

      (Carroll and Scott, 1986)

      The denticle belts of the mesothoracic segment, A1, A3, A5 and A7 are deleted, with the deletion extending through the naked cuticle in front of the denticle belts, and into the posterior half of the remaining denticle belts. The deleted regions are replaced by mirror-image duplications of the remaining pattern elements.

      (Gergen and Wieschaus, 1985)

      strong hypomorph

      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer

      Wieschaus.

      Comments
      Comments

      Embryos mosaic for run28 show that the effect of run on segment pattern is largely autonomous.

      (Gergen and Wieschaus, 1985)

      prd RNA expression has been studied in run28 embryos.

      (Baumgartner and Noll, 1990)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (5)
      References (16)