FlyBase Allele Report: Dmel\Me[1]

General Information

Symbol

Dmel\Me¹

Species

D. melanogaster

Name

FlyBase ID

FBal0012129

Feature type

allele

Associated gene

Associated Insertion(s)

Carried in Construct

Key Links

Allele class

Mutagen

X ray

Nature of the Allele

Allele class

Mutagen

X ray

Progenitor genotype

Cytology

Description

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

lethal | recessive

(Carpenter, 1998.11.24, Lindsley and Grell, 1968)

Phenotype Manifest In

eye

(Carpenter, 1998.11.24)

Detailed Description

Statement

Reference

Me³ phenotype weaker than Me¹ and unscoreable in cn. Me³ lethal over Me¹.

(Carpenter, 1998.11.24)

The Me^65d/Me¹ combination is lethal.

(Lindsley and Grell, 1968)

Eye has watered-silk, shimmering, iridescent pattern owing to a ring of six flecks around normal fleck. Eye color brownish and translucent; 79% normal red pigment and 85% normal brown pigment (Nolte, 1955). Larval Malpighian tubes considerably lighter in color than normal but mutant classifiable with difficulty (Brehme and Demerec, 1942). Contains a modifier of dominance of dp such that dp/+; Me/+ has truncated wings. Classifiable in single dose in triploids (Schultz, 1934). Homozygous lethal. Me/In(3L)P is viable. RK1A.

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

NOT Enhancer of

Statement

Reference

Me[+]/Me¹ is a non-enhancer of wing vein | ectopic phenotype of Snr1^E1

(Marenda et al., 2004)

NOT Suppressor of