FB2024_03 , released June 25, 2024
Allele: Dmel\Trls2325
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General Information
Symbol
Dmel\Trls2325
Species
D. melanogaster
Name
FlyBase ID
FBal0011150
Feature type
allele
Associated gene
Dmel\Trl
Associated Insertion(s)
P{lacW}s2325
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
P-element activity
Progenitor genotype
Associated Insertion(s)
P{lacW}s2325
Cytology
Description
Allele components
Component
Use(s)
Inserted element
P{lacW}
Encoded product / tool
lacZ
Tagged with
Tag:NLS(P)
Mutations Mapped to the Genome
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Heterozygotes show a direct effect on the shape of the wing.

      (Dworkin and Gibson, 2006)

      Heterozygotes show the formation of "granular" chromatin during interphase and mitosis and high proportions of cells (which are arrested at the G2/M boundary) have hypercondensed chromatin. Cells with abnormal chromosome segregation are also seen. Heterozygous females have egg chambers with an abnormal number of trophocytes and defects in chromatin condensation.

      (Trunova et al., 2001)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      NOT Suppressor of
      Statement
      Reference

      Trls2325 is a non-suppressor of visible phenotype of MycUAS.cZa, Scer\GAL4GMR.PF

      (Secombe et al., 2007)
      Phenotype Manifest In
      NOT Suppressor of
      Statement
      Reference

      Trls2325 is a non-suppressor of eye phenotype of MycUAS.cZa, Scer\GAL4GMR.PF

      (Secombe et al., 2007)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      The formation of extra sex combs on the second and third legs in Pc4/+ flies is not enhanced by Trls2325.

      (Kehle et al., 1998)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (2)
      Notes on Origin
      Discoverer

      M. Scott.

      Comments
      Comments

      Complements: Mpcp00564.

      (BDGP Project Members, 1994-1999)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (8)
      Reported As
      Symbol Synonym
      S2325
      (Dworkin and Gibson, 2006)
      TrlP2088
      (Kehle et al., 1998)
      TrlS2325
      (Secombe et al., 2007)
      Trls2325
      (Gaskill et al., 2023, Di Stefano et al., 2011, Dworkin and Gibson., 2006)
      Trll(3)s2325
      (Katokhin et al., 2001)
      Trls2325
      (Trunova et al., 2001)
      l(3)s2325
      (Spradling et al., 1999)
      l(3)s2325s2325
      Name Synonyms
      Secondary FlyBase IDs
        References (13)