FB2024_03 , released June 25, 2024
Allele: Dmel\pros10419
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General Information
Symbol
Dmel\pros10419
Species
D. melanogaster
Name
FlyBase ID
FBal0009621
Feature type
allele
Associated gene
Dmel\pros
Associated Insertion(s)
P{PZ}pros10419
Carried in Construct
Also Known As
l(3)10419, pros-lacZ
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
P-element activity
(Kauffmann et al., 1996, Treisman and Rubin, 1996)
Progenitor genotype
Associated Insertion(s)
P{PZ}pros10419
Cytology
Description

P{PZ} insertion upstream of the transcription start site.

(Kauffmann et al., 1996)
Allele components
Component
Use(s)
Inserted element
P{PZ}
Encoded product / tool
lacZ
Tagged with
Tag:NLS(P)
Mutations Mapped to the Genome
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Marker and axonal projection analysis of R7 cells in pros10419 and mutants indicates partial transformation of R7 photoreceptors cells towards and R8 photoreceptors cell fate.

      (Cook et al., 2003)

      Severe defasciculation of the recurrent nerve, compacting of the esophageal ganglia and disorganisation of the frontal connectives.

      (Forjanic et al., 1997)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Enhancer of
      Statement
      Reference

      pros10419 is an enhancer of phenotype of sina4

      (Kauffmann et al., 1996)
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer

      A. Spradling.

      Comments
      Comments

      Complements: l(3)0462905275. Complements: l(3)0965609656.

      (BDGP Project Members, 1994-1999)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      l(3)10419
      (Spradling et al., 1999, Forjanic et al., 1997)
      pros10419
      (Cook, 2006.10.1, Sarfare et al., 2005)
      Name Synonyms
      Secondary FlyBase IDs
        References (12)