Polytene chromosomes normal.
Homozygous females are transformed to intersexes under restrictive and semi-restrictive temperatures (29oC and 25oC). Mutant males show a weak transformation to intersexuality in the sixth sternite has bristles. Surviving daughters of homozygotes and transheterozygotes raised at semi-restrictive temperatures show a high frequency of morphological defects not seen in sons. Maternal effect female lethality is enhanced by Sxlf1. Severely restrictive conditions (29oC for more than 2 days) reveals maternal sex-nonspecific lethality for all heteroallelic combinations except her3/her2 : embryos show defect in gastrulation and differentiation of the cuticles.
Homozygous females produce 1 daughter to 5.5 sons. Abnormal sex ratio caused by inviability of females. l(2)mat does not seem to be allelic to da, which has a similar effect. RK3.
Heat induced expression of herhs.PL rescues female semi-sterility.
Redfield, Feb. 1923.
Relative severity of the effects on female and male sexual differentiation is her3 > her1 > her2 > hermat-1. Relative severity of the effects on viability is her3 > her1 = her2 > hermat-1.
Severely defective in maternal her functions but wild type in zygotic her functions.