FB2024_03 , released June 25, 2024
Allele: Dmel\hop33
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General Information
Symbol
Dmel\hop33
Species
D. melanogaster
Name
FlyBase ID
FBal0005544
Feature type
allele
Associated gene
Dmel\hop
Associated Insertion(s)
Carried in Construct
Also Known As
hopM75
Key Links
Allele class

amorphic allele - genetic evidence

Mutagen
Nature of the Allele
Allele class

amorphic allele - genetic evidence

(Perrimon and Mahowald, 1986)
Mutagen
ethyl nitrosourea
Progenitor genotype
Cytology
Description
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      hop25/hop33 non-fused egg chambers often have extra polar follicle cells (having 3 or 4 cells rather than the normal number of 2 polar cells at both the anterior and posterior ends of the egg chamber). At stage 8/9, 93% of egg chambers have extra polar cells at the anterior end and 67% of egg chambers have extra polar cells at the posterior end. The number of interfollicular cells is reduced. The extra polar cells do not appear to be due to continued proliferation of the polar cell population.

      (McGregor et al., 2002)

      70% viable in transheterozygous combination with hop25.

      (Harrison et al., 1998)

      Paternal rescue of the maternal effect. Germline clone analysis demonstrates that embryos have one abdominal segment missing and A4 appears wider than wild type, and partial or complete fusion of T1 and T2.

      (Perrimon and Mahowald, 1986)

      larval/pupal lethal hop33/hop25 100% viable

      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Enhanced by
      Statement
      Reference

      hop33/hop25 has partially lethal phenotype, enhanceable by upd1YM55

      (Harrison et al., 1998)
      Other
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Viability of hop25/hop33 flies is reduced if the flies also carry osupd-4.

      (Harrison et al., 1998)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer

      Voelker.

      Comments
      Comments

      Fully complement hop25.

      (Perrimon and Mahowald, 1986)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (4)
      Reported As
      Symbol Synonym
      hop33
      hopM75
      (Rawlings et al., 2004, McGregor et al., 2002, Harrison et al., 1998)
      l(1)M75
      l(1)hopM75
      (Perrimon and Mahowald, 1986)
      Name Synonyms
      Secondary FlyBase IDs
        References (4)