FlyBase Allele Report: Dmel\Delta[CS20]

General Information

Symbol

Dmel\Delta^CS20

Species

D. melanogaster

Name

FlyBase ID

FBal0002546

Feature type

allele

Associated gene

Dmel\Delta

Associated Insertion(s)

Carried in Construct

Also Known As

Dl^CS

Key Links

Allele class

hypomorphic allele - genetic evidence

Mutagen

Nature of the Allele

Allele class

hypomorphic allele - genetic evidence

(Shepard et al., 1989)

Mutagen

spontaneous

(Shepard et al., 1989)

ethyl methanesulfonate

(Leviten and Posakony, 1996)

Progenitor genotype

Cytology

Description

95.5 to 96.8 kb

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

lethal | recessive

(Leviten and Posakony, 1996)

Phenotype Manifest In

leg

(Bender et al., 1993)

scutellar bristle | increased number

(Wildonger and Mann, 2005)

wing

(Bender et al., 1993)

Detailed Description

Statement

Reference

Dl^CS20/+ flies have a slightly increased number of scutellar macrochaetae compared to wild type.

(Wildonger and Mann, 2005)

The Dl^6B/Dl^CS20 transheterozygotes show severe defects in wings and legs but relatively robust fertility and have high pupal and adult viability. Ovaries are only mildly affected, even at 29^oC.

(Bender et al., 1993)

Moderate phenotypic reversion: 150--250 facets per eye. Wing venation phenotype. Lethal when heterozygous with Dl³.

(Shepard et al., 1989)

moderate allele

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Enhanced by

Statement

Reference

Delta^CS20 has scutellar bristle | increased number phenotype, enhanceable by Df(2R)nvy^PDFKG1/+

(Wildonger and Mann, 2005)

Enhancer of

Statement

Reference

Delta^CS20 is an enhancer of phenotype of Brd¹

(Leviten and Posakony, 1996)

Delta^CS20 is an enhancer of phenotype of Brd³

(Leviten and Posakony, 1996)

Additional Comments

Genetic Interactions

Statement

Reference

The number of extra scutellar macrochaetae is enhanced in Dl^CS20/+; Df(2R)nvy^PDFKG1/+ double mutants, compared to Dl^CS20/+ single mutants.

(Wildonger and Mann, 2005)

Extragenic suppressor of the N^spl-1-E(spl)¹ interaction.

(Shepard et al., 1989)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

Muskavitch.

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (4)

Reported As

Symbol Synonym

Delta^CS20

Dl^CS20

Dl^CS

(Wildonger and Mann, 2005, Stone and Posakony, 2001, Leviten and Posakony, 1996, Bender et al., 1993, Parody and Muskavitch, 1993)

Dl^cs

(Stone and Posakony, 2002)

Name Synonyms

Secondary FlyBase IDs

References (9)

Report Sections

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