FlyBase Allele Report: Dmel\cin[1]

General Information

Symbol

Dmel\cin¹

Species

D. melanogaster

Name

FlyBase ID

FBal0001662

Feature type

allele

Associated gene

Dmel\cin

Associated Insertion(s)

Carried in Construct

Key Links

Allele class

Mutagen

ethyl methanesulfonate

Nature of the Allele

Allele class

Mutagen

ethyl methanesulfonate

Progenitor genotype

Cytology

Description

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal eye color

(Lindsley and Zimm, 1992)

female sterile | recessive

(Wittle et al., 1999)

lethal | maternal effect

(Lindsley and Zimm, 1992)

lethal - all die during embryonic stage | rescuable maternal effect

(Wittle et al., 1999)

some die during embryonic stage | rescuable maternal effect

(Wittle et al., 1999)

Phenotype Manifest In

Detailed Description

Statement

Reference

cin¹/Y and cin¹/cin¹ embryos of cin¹/cin¹ mothers almost completely lethal; rare surviving adults have reddish-brown eyes; both survival and normal eye pigmentation affected by the presence of cin⁺ in either the mother or the zygote.

(Lindsley and Zimm, 1992)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressed by

Statement

Reference

cin¹ has female sterile phenotype, suppressible by Atha\cnx1^hs.PW

(Wittle et al., 1999)

Other

Statement

Reference

Atha\cnx1^hs.PW, cin¹ has female fertile phenotype

(Wittle et al., 1999)

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Aldehyde oxidase defect (indicative of MoCF defect) rescued by one copy of Atha\cnx1^hs.PW, carried in P{hsp70-cnx1.W}. Atha\cnx1^hs.PW can also rescue the 'female sterile' maternal effect lethality of cin¹.

(Wittle et al., 1999)

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (12)

Bloomington

4554

C(1)RA, cin¹ y¹/Dp(1;Y)y⁺/Sxl^K1274-1 v²⁴

1305

C(1)RA, cin¹ y¹/Dp(1;Y)y⁺/cin¹ y¹ w¹