FB2024_03 , released June 25, 2024
Aberration: Dmel\Df(3R)5C1
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General Information
Symbol
Df(3R)5C1
Species
D. melanogaster
Name
FlyBase ID
FBab0026864
Feature type
chromosomal_deletion
Computed Breakpoints include

93E-93F;94C-94D

Features within 93E--94D
Sequence coordinates
Member of large scale dataset(s)
Nature of Aberration
Cytological Order
Progenitor
P{lacZ.ry+}locorC56
(Granderath et al., 1999, Klämbt, 1996.12.4)
Mutagen
P-element activity
(Klämbt, 1996.12.4)
Class of aberration (relative to wild type)
chromosomal_deletion
(FlyBase, 2007)
Class of aberration (relative to progenitor)
chromosomal_deletion
(Granderath et al., 1999, Klämbt, 1996.12.4)
Breakpoints

93E-93F;94C-94D

(Granderath et al., 1999, Klämbt, 1996.12.4)
Causes alleles
Carries alleles
Transposon Insertions
Formalized genetic data

bk2 << pnt

Genetic mapping information
Comments
Comments on Cytology

All limits from polytene analysis (FBrf0091283)

Sequence Crossreferences
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
Gene Deletion and Duplication Data
Genes Deleted / Disrupted
Complementation Data
Completely deleted / disrupted
loco
(Granderath et al., 1999)
Nrx-1
(Li et al., 2007)
Partially deleted / disrupted
Molecular Data
Completely deleted
Partially deleted
Genes NOT Deleted / Disrupted
Complementation Data
 
lmd
(Ruiz-Gomez et al., 2002)
pnt
(Klämbt, 1996.12.4)
Molecular Data
 
Genes Duplicated
Complementation Data
Completely duplicated
Partially duplicated
Molecular Data
Completely duplicated
Partially duplicated
Genes NOT Duplicated
Complementation Data
 
Molecular Data
 
Affected Genes Inferred by Location
    Phenotypic Data
    In combination with other aberrations
    NOT in combination with other aberrations

    One copy of Df(3R)5C1 is unable to suppress position effect variegation (PEV) at the w locus caused by In(1)wm4.

    One copy of Df(3R)5C1 moderately suppresses the telomeric position effect (TPE) in stocks carrying a variegating P{hsp26-pt-T}39C-5 insertion at the telomere of the left arm of chromosome two.

    (Doheny et al., 2008)

    Embryos homozygous for Df(3R)5C1 contain numerous unclustered apoptotic cells (assayed using acridine orange staining), in contrast to wild-type embryos where the apoptotic cells are seen to cluster together due to their engulfment by hemocytes.

    (Krieser et al., 2007)
    Stocks (3)
    Notes on Origin
    Discoverer

    S. Granderath.

    (Klämbt, 1996.12.4)
     
    Balancer / Genotype Variants of the Aberration
     
    Separable Components
     
    Other Comments
     

    The Df(3R)5C1 chromosome may act as a dominant suppressor of telomeric silencing (assayed using the effect of the chromosome on the eye colour phenotype of flies carrying "P{wvar}KR3-2", a stable "brown-red" variant of the P{3'WP-2,wvar}2Lt insertion), but the eye colour phenotype in the presence of Df(3R)5C1 overlaps the eye colour phenotype in a wild-type background so it cannot be unequivocally demonstrated that the deficiency chromosome uncovers a suppressor of telomeric silencing. In addition, any suppression is a false positive result (the suppressor is not within the bounds of the deficient region) because the region of the deficiency is covered by one or more nonsuppressing deficiencies.

    (Mason et al., 2004)
    Synonyms and Secondary IDs (3)
    Reported As
    Symbol Synonym
    Df(3R)5C1
    (Ramesh et al., 2021, Banerjee et al., 2017, Rui et al., 2017, Chen et al., 2012, Krieser et al., 2007, Li et al., 2007)
    Df(3R)93E-F; 94C-D
    (Doheny et al., 2008)
    Nrx-1Df
    (Owald et al., 2012)
    Name Synonyms
    Secondary FlyBase IDs
      References (14)