FB2024_03 , released June 25, 2024
Physical Interaction report
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General Information
Interaction Type
physical association
Interacting Genes
Oxp, His3
FlyBase ID
FBig0000122012
Interaction Network
Interactions Browser links
Oxp network
His3 network
esyN Network Diagram
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Protein
RNA
Selected Interactor(s)
Common Interactor(s)
Reported Interactions
FBrf0256008-1.ITC
Reference
Jin et al., 2023
Description
physical association
Assay
Collection
Source/Stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
Oxp 

Oxp

bait
Oxp 
Oxp 
His3 

H3K9me3

prey
His3 
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Oxp 
chromodomain
sufficient binding region
aa 18-84

coordinates relative to Oxp-PA

Oxp 
interaction residue 44
sufficient binding region
aa 44

E44S; coordinates relative to Oxp-PA

His3 
interaction domain
sufficient binding region
aa 1-10

Trimethylated lysine 9 modification.

Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Interaction in vitro; bait produced as a recombinant fusion protein in bacterial system; prey chemically synthesized.

(Jin et al., 2023)
FBrf0256008-3.XC
Reference
Jin et al., 2023
Description
physical association
Assay
Collection
Source/Stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
Oxp 

Oxp

neutral component
Oxp 
Oxp 

Oxp

neutral component
Oxp 
Oxp 

Oxp

neutral component
His3 
His3 

H3K9me3

neutral component
His3 

H3K9me3

neutral component
His3 
His3 

H3K9me3

neutral component
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Oxp 
chromodomain
sufficient binding region
aa 18-84

coordinates relative to Oxp-PA

His3 
interaction domain
sufficient binding region
aa 1-10

Trimethylated lysine 9 modification.

Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Interaction in vitro; first protein produced as a recombinant fusion protein in bacterial system; second protein chemically synthesized

(Jin et al., 2023)
External Crossreferences and Linkouts ( 0 )
References (1)