FlyBase Gene Report: Dmel\oxt

General Information

Symbol

Dmel\oxt

Species

D. melanogaster

Name

peptide O-xylosyltransferase

Annotation Symbol

CG32300

Feature Type

protein_coding_gene

FlyBase ID

FBgn0015360

Gene Model Status

Current

Stock Availability

8 publicly available

Enzyme Name (EC)

protein xylosyltransferase (2.4.2.26)

Gene Summary

peptide O-xylosyltransferase (oxt) encodes an enzyme that catalyzes the first xylose of the linkage region of glycosaminoglycan (GAG). Through GAG synthesis, the product of oxt is involved in several signaling pathways mediated by GAGs in development. [Date last reviewed: 2019-03-14] (FlyBase Gene Snapshot)

All Summaries

Gene Snapshot
Alliance
Auto summary
Gene Group
UniProtKB
Interactive Fly

Also Known As

dOXT, dXylT

Key Links

Genomic Location

Cytogenetic map

62D4-62D4

Sequence location

3L:2,258,839..2,262,664 [-]

Recombination map

3-2

RefSeq locus

NT_037436 REGION:2258839..2262664

Sequence

Get Decorated FASTA

Genomic Maps

JBrowse

Other Genome Views

The following external sites may use different assemblies or annotations than FlyBase.

Function

Gene Ontology (GO) Annotations (8 terms)

Molecular Function (1 term)

Terms Based on Experimental Evidence (1 term)

CV Term

Evidence

References

enables protein xylosyltransferase activity

inferred from direct assay

(Brunner et al., 2006, Wilson, 2002)

Terms Based on Predictions or Assertions (1 term)

CV Term

Evidence

References

enables protein xylosyltransferase activity

inferred from biological aspect of ancestor with PANTHER:PTN005271747

(GO Reference Genome Project, 2011-)

inferred from electronic annotation with InterPro:IPR043538

(InterPro Project Members, 2004-)

Biological Process (6 terms)

Terms Based on Experimental Evidence (5 terms)

CV Term

Evidence

References

involved_in chondroitin sulfate metabolic process

inferred from mutant phenotype

(Yamamoto-Hino et al., 2015)

involved_in chondroitin sulfate proteoglycan biosynthetic process

inferred from direct assay

(Wilson, 2002)

involved_in D-xylose metabolic process

inferred from direct assay

(Wilson, 2002)

involved_in heparan sulfate proteoglycan biosynthetic process

inferred from direct assay

(Wilson, 2002)

involved_in heparan sulfate proteoglycan metabolic process

inferred from mutant phenotype

(Yamamoto-Hino et al., 2015)

Terms Based on Predictions or Assertions (3 terms)

CV Term

Evidence

References

involved_in chondroitin sulfate proteoglycan biosynthetic process

inferred from biological aspect of ancestor with PANTHER:PTN005271747

(GO Reference Genome Project, 2011-)

involved_in heparan sulfate proteoglycan biosynthetic process

inferred from biological aspect of ancestor with PANTHER:PTN005271747

(GO Reference Genome Project, 2011-)

involved_in proteoglycan biosynthetic process

inferred from electronic annotation with InterPro:IPR043538

(InterPro Project Members, 2004-)

Cellular Component (1 term)

Terms Based on Experimental Evidence (0 terms)

Terms Based on Predictions or Assertions (1 term)

CV Term

Evidence

References

located_in membrane

non-traceable author statement

(Wilson, 2002)

inferred from electronic annotation with InterPro:IPR003406

(InterPro Project Members, 2004-)

Gene Group (FlyBase)

XYLOSYLTRANSFERASES

Protein Family (UniProt)

Belongs to the glycosyltransferase 14 family. XylT subfamily. (Q7KVA1)

Protein Signatures (InterPro)

Catalytic Activity (EC/Rhea)

protein xylosyltransferase activity

L-seryl-[protein] + UDP-alpha-D-xylose = 3-O-(beta-D-xylosyl)-L-seryl- [protein] + H(+) + UDP (2.4.2.26)

RHEA 50192:

Summaries

Gene Snapshot

Gene Group (FlyBase)

XYLOSYLTRANSFERASES -: Xylosyltransferases catalyze the transfer of a xylosyl group to an acceptor molecule, which may be a lipid, carbohydrate, protein or proteoglycan.

Protein Function (UniProtKB)

Catalyzes the first step in biosynthesis of glycosaminoglycan. Transfers D-xylose from UDP-D-xylose to specific serine residues of the core protein. Initial enzyme in the biosynthesis of chondroitin sulfate and dermatan sulfate proteoglycans in fibroblasts and chondrocytes.

(UniProt, Q7KVA1)

Gene Model and Products

Number of Transcripts

Number of Unique Polypeptides

Please see the JBrowse view of Dmel\oxt for information on other features

To submit a correction to a gene model please use the Contact FlyBase form

Protein Domains (via Pfam)

Isoform displayed:

Pfam protein domains

InterPro name

classification

start

end

Protein Domains (via SMART)

Isoform displayed:

SMART protein domains

InterPro name

classification

start

end

Structure

Protein 3D structure (Predicted by AlphaFold) (AlphaFold entry Q7KVA1)

If you don't see a structure in the viewer, refresh your browser.

Model Confidence:

Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)

AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Some regions with low pLDDT may be unstructured in isolation.

Experimentally Determined Structures

Crossreferences

Comments on Gene Model

Low-frequency RNA-Seq exon junction(s) not annotated.

Gene model reviewed during 5.45

Sequence Ontology: Class of Gene

nuclear_gene

protein_coding_gene

Transcript Data

Annotated Transcripts

Name

FlyBase ID

RefSeq ID

Length (nt)

Assoc. CDS (aa)

oxt-RB

FBtr0072904

NM_139448

3380

876

Additional Transcript Data and Comments

Reported size (kB)

Comments

External Data

Crossreferences

Polypeptide Data

Annotated Polypeptides

Name

FlyBase ID

Predicted MW (kDa)

Length (aa)

Theoretical pI

UniProt

RefSeq ID

GenBank

oxt-PB

FBpp0072782

99.1

876

8.18

Q7KVA1

NP_647705

AAF47625

Polypeptides with Identical Sequences

There is only one protein coding transcript and one polypeptide associated with this gene

Additional Polypeptide Data and Comments

Reported size (kDa)

Comments

External Data

Crossreferences

InterPro - A database of protein families, domains and functional sites

Linkouts

Sequences Consistent with the Gene Model

Mapped Features

Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\oxt using the Feature Mapper tool.

External Data

Crossreferences

Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.

oxt_1

Linkouts

Expression Data

Testis-specificity index

The testis specificity index was calculated from modENCODE tissue expression data by Vedelek et al., 2018 to indicate the degree of testis enrichment compared to other tissues. Scores range from -2.52 (underrepresented) to 5.2 (very high testis bias).

0.65

Transcript Expression

in situ

Stage

Tissue/Position (including subcellular localization)

Reference

embryonic stage 1 -- 3

organism

Comment: maternally deposited

(Fisher et al., 2012)

embryonic stage 4 -- 6

organism

(Fisher et al., 2012)

embryonic stage 7 -- 8

organism | ubiquitous

(Fisher et al., 2012)

embryonic stage 9 -- 10

organism | ubiquitous

(Fisher et al., 2012)

embryonic stage 11 -- 12

organism | ubiquitous

(Fisher et al., 2012)

embryonic stage 13 -- 16

organism | ubiquitous

(Fisher et al., 2012)

Additional Descriptive Data

Marker for

Subcellular Localization

CV Term

Polypeptide Expression

mass spectroscopy

Stage

Tissue/Position (including subcellular localization)

Reference

adult stage

adult head

• membrane

(Aradska et al., 2015)

day 5 of adulthood & male -- day 7 of adulthood & male

spermatozoon

(Wasbrough et al., 2010)

Additional Descriptive Data

Marker for

Subcellular Localization

CV Term

Evidence

References

Expression Deduced from Reporters

High-Throughput Expression Data

Associated Tools

JBrowse - Visual display of RNA-Seq signals

View Dmel\oxt in JBrowse

RNA-Seq by Region - Search RNA-Seq expression levels by exon or genomic region

View exonic expression by developmental stage for Dmel\oxt

View exonic expression by tissue for Dmel\oxt

Bulk Downloads

RNA-Seq RPKM values for all genes

Reference

See Gelbart and Emmert, 2013 for analysis details and data files for all genes.

Developmental Proteome: Life Cycle

Developmental Proteome: Embryogenesis

External Data and Images

Linkouts

BDGP expression data - Patterns of gene expression in Drosophila embryogenesis

FBgn0015360

DRscDB - A single-cell RNA-seq resource for data mining and data comparison across species

38288/tissue=All

EMBL-EBI Single Cell Expression Atlas - Single cell expression across species

FBgn0015360

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

FBgn0015360

FlyAtlas2 - A Drosophila melanogaster expression atlas with RNA-Seq, miRNA-Seq and sex-specific data

FBgn0015360

Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns

CG32300

Flygut - An atlas of the Drosophila adult midgut

FBgn0015360

Images

FlyBase Wiki

Image Based Resources

Alleles, Insertions, Transgenic Constructs, and Aberrations

Classical and Insertion Alleles ( 3 )

For All Classical and Insertion Alleles Show

Other relevant insertions

Transgenic Constructs ( 8 )

For All Alleles Carried on Transgenic Constructs Show

Transgenic constructs containing/affecting coding region of oxt

Transgenic constructs containing regulatory region of oxt

Aberrations (Deficiencies and Duplications) ( 0 )

Inferred from experimentation ( 0 )

Inferred from location ( 0 )

Variants

Variant Molecular Consequences

Alleles Representing Disease-Implicated Variants

Phenotypes

For more details about a specific phenotype click on the relevant allele symbol.

Lethality

Allele

lethal, with Scer\GAL4^Act5C.PU

oxt^RNAi.UAS.cYa

viable, with Dcr-2^UAS.cDa, Scer\GAL4^elav.PLu

oxt^GD2261

viable, with Scer\GAL4^Mef2.PR

oxt^GD2261

viable, with Scer\GAL4^pnr-MD237

oxt^GD2261

viable, with Scer\GAL4^tin.CΔ4

oxt^GD2261

Other Phenotypes

Allele

visible, with Scer\GAL4^GMR.PS

oxt^RNAi.UAS

Phenotype manifest in

Allele

eye, with Scer\GAL4^GMR.PS

oxt^RNAi.UAS

eye | pharate adult stage, with Scer\GAL4^GMR.PF

oxt^RNAi.UAS.cUa

ommatidium, with Scer\GAL4^GMR.PS

oxt^RNAi.UAS

scutellar bristle | pharate adult stage, with Scer\GAL4^ap-md544

oxt^RNAi.UAS.cUa

wing vein | ectopic, with Scer\GAL4^A9

oxt^RNAi.UAS.cYa

wing vein | ectopic, with Scer\GAL4^Bx-MS1096

oxt^RNAi.UAS.cYa

wing vein | ectopic, with Scer\GAL4^sd-SG29.1

oxt^RNAi.UAS.cYa

Orthologs

Downloads

Download All DIOPT Orthologs

Human Orthologs (via DIOPT v9.1)

Species\Gene Symbol

Score

Best Score

Best Reverse Score

Source

Alignment

Complementation?

Transgene?

Homo sapiens (Human) (11)

Hsap\XYLT1

14 of 14

Yes

Hsap\XYLT2

13 of 14

Yes

Hsap\GCNT1

3 of 14

Yes

Hsap\GCNT2

3 of 14

Yes

Hsap\GCNT3

3 of 14

Yes

Hsap\WSCD2

3 of 14

Hsap\GCNT4

2 of 14

Yes

Hsap\GCNT7

2 of 14

Yes

Hsap\WSCD1

2 of 14

Hsap\KREMEN1

1 of 14

Yes

Hsap\KREMEN2

1 of 14

Yes

Model Organism Orthologs (via DIOPT v9.1)

Species\Gene Symbol

Score

Best Score

Best Reverse Score

Source

Alignment

Complementation?

Transgene?

Rattus norvegicus (Norway rat) (9)

Rnor\Xylt1

13 of 14

Yes

Rnor\Xylt2

13 of 14

Yes

Rnor\Gcnt1

3 of 14

Yes

Rnor\Gcnt2

3 of 14

Yes

Rnor\Gcnt7

3 of 14

Yes

Rnor\Gcnt3

2 of 14

Yes

Rnor\Wscd1

2 of 14

Rnor\Wscd2

2 of 14

Rnor\Gcnt4

1 of 14

Yes

Mus musculus (laboratory mouse) (11)

Mmus\Xylt1

13 of 14

Yes

Mmus\Xylt2

13 of 14

Yes

Mmus\Gcnt1

3 of 14

Yes

Mmus\Gcnt2

3 of 14

Yes

Mmus\Gcnt3

3 of 14

Yes

Mmus\Gcnt4

3 of 14

Yes

Mmus\Gcnt7

3 of 14

Yes

Mmus\Wscd2

3 of 14

Mmus\Wscd1

2 of 14

Mmus\Kremen1

1 of 14

Yes

Mmus\Kremen2

1 of 14

Yes

Xenopus tropicalis (Western clawed frog) (19)

Xtro\xylt1

11 of 13

Yes

Xtro\xylt2

7 of 13

Yes

6 of 13

2 of 13

1 of 13

1 of 13

Yes

Xtro\gcnt2.2

1 of 13

Yes

Xtro\gcnt3

1 of 13

Xtro\grm7

1 of 13

Xtro\hopx

1 of 13

Yes

Xtro\hsf2.2

1 of 13

Xtro\kif24

1 of 13

Yes

Xtro\LOC100490667

1 of 13

Yes

Xtro\LOC100491539

1 of 13

Yes

Xtro\mfsd2b

1 of 13

Yes

Xtro\nup160

1 of 13

Yes

Xtro\wscd1

1 of 13

Xtro\wscd2

1 of 13

Xtro\XB990816

1 of 13

Yes

Danio rerio (Zebrafish) (10)

Drer\xylt1

14 of 14

Yes

Drer\xylt2

13 of 14

Yes

Drer\gcnt3

3 of 14

Yes

Drer\gcnt4a

3 of 14

Yes

Drer\gcnt7

3 of 14

Yes

Drer\wscd2

3 of 14

Drer\gcnt4b.1

2 of 14

Yes

Drer\gcnt4b.2

2 of 14

Yes

Drer\wscd1b

2 of 14

Drer\kremen1

1 of 14

Yes

Caenorhabditis elegans (Nematode, roundworm) (21)

Cele\sqv-6

12 of 14

Yes

Cele\F30A10.4

2 of 14

Yes

Cele\F35H8.2

2 of 14

Yes

Cele\gly-1

2 of 14

Yes

Cele\gly-16

2 of 14

Yes

Cele\gly-17

2 of 14

Yes

Cele\gly-18

2 of 14

Yes

Cele\gly-19

2 of 14

Yes

Cele\H41C03.3

2 of 14

Yes

Cele\R07C3.3

2 of 14

Yes

Cele\T09E11.6

2 of 14

Yes

Cele\T09E11.9

2 of 14

Yes

Cele\T14B4.9

2 of 14

Yes

Cele\T27F6.1

2 of 14

Yes

Cele\T28F3.9

2 of 14

Yes

Cele\ZK1225.2

2 of 14

Yes

Cele\C34H4.5

1 of 14

Cele\F26D2.3

1 of 14

Yes

Cele\gly-15

1 of 14

Yes

Cele\R07B7.6

1 of 14

Yes

Cele\Y51H4A.25

1 of 14

Yes

Anopheles gambiae (African malaria mosquito) (2)

Agam\AgaP_AGAP005811

12 of 12

Yes

Agam\AgaP_AGAP005810

6 of 12

Yes

Arabidopsis thaliana (thale-cress) (11)

Atha\AT1G53100

6 of 13

Yes

Atha\AT2G37585

6 of 13

Yes

Atha\AT3G15350

6 of 13

Yes

Atha\AT4G03340

6 of 13

Yes

Atha\AT4G27480

6 of 13

Yes

Atha\AT5G15050

6 of 13

Yes

Atha\AT5G39990

6 of 13

Yes

Atha\AT1G71070

5 of 13

Yes

Atha\AT3G24040

5 of 13

Yes

Atha\UNE7

5 of 13

Yes

Atha\AT1G03520

1 of 13

Yes

Saccharomyces cerevisiae (Brewer's yeast) (4)

Scer\SLG1

1 of 13

Yes

Scer\WSC2

1 of 13

Yes

Scer\WSC3

1 of 13

Yes

Scer\WSC4

1 of 13

Yes

Schizosaccharomyces pombe (Fission yeast) (1)

Spom\wsc1

1 of 12

Yes

Escherichia coli (enterobacterium) (0)

Other Organism Orthologs (via OrthoDB)

Data provided directly from OrthoDB:oxt. Refer to their site for version information.

Paralogs

Downloads

Download All DIOPT Paralogs

Paralogs (via DIOPT v9.1)

Gene Symbol

Score

Source

Alignment

Drosophila melanogaster (Fruit fly) (1)

CG9164

2 of 13

Human Disease Associations

FlyBase Human Disease Model Reports

Alzheimer disease, susceptibility to (postulated), XYLT1-related

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Allele

Disease

Evidence

References

Potential Models Based on Orthology ( 4 )

Human Ortholog

Disease

Evidence

References

XYLT1; xylosyltransferase 1

model of Desbuquois dysplasia

IEA

(FlyBase, 2019-)

model of pseudoxanthoma elasticum

IEA

(FlyBase, 2019-)

XYLT2; xylosyltransferase 2

model of pseudoxanthoma elasticum

IEA

(FlyBase, 2019-)

GCNT2; glucosaminyl (N-acetyl) transferase 2 (I blood group)

model of cataract 13 with adult i phenotype

IEA

(FlyBase, 2019-)

Modifiers Based on Experimental Evidence ( 2 )

Allele

Disease

Interaction

References

oxt^RNAi.UAS

exacerbates tauopathy

modeled by Hsap\MAPT^V337M.UAS

(Shulman et al., 2014)

oxt^G4946

ameliorates tauopathy

modeled by Hsap\MAPT^V337M.UAS

(Shulman et al., 2014)

Disease Associations of Human Orthologs (via DIOPT v9.1 and OMIM)

Note that ortholog calls supported by only 1 or 2 algorithms (DIOPT score < 3) are not shown.

Homo sapiens (Human)

Gene name

Score

OMIM

OMIM Phenotype

DO term

Complementation?

Transgene?

XYLT1; xylosyltransferase 1

14 of 14

608124

XYLT2; xylosyltransferase 2

13 of 14

608125

pseudoxanthoma elasticum

GCNT1; glucosaminyl (N-acetyl) transferase 1

3 of 14

600391

GCNT2; glucosaminyl (N-acetyl) transferase 2 (I blood group)

3 of 14

600429

cataract 13 with adult i phenotype

GCNT3; glucosaminyl (N-acetyl) transferase 3, mucin type

3 of 14

606836

WSCD2; WSC domain containing 2

3 of 14

619253

Functional Complementation Data

Functional complementation data is computed by FlyBase using a combination of the orthology data obtained from DIOPT and OrthoDB and the allele-level genetic interaction data curated from the literature.

Interactions

Summary of Physical Interactions

esyN Network Diagram

Interactions Browser

MIST Molecular Interaction Search Tool

Summary of Genetic Interactions

esyN Network Diagram

Show/hide secondary interactors
(data from AllianceMine provided by esyN)

esyN Network Key:

Suppression

Enhancement

View in Interactions Browser View in MIST tool (external link)

Please look at the allele data for full details of the genetic interactions

Starting gene(s)

Interaction type

Interacting gene(s)

Reference

oxt

enhanceable

β3GalTII

(Ueyama et al., 2008)

Starting gene(s)

Interaction type

Interacting gene(s)

Reference

β3GalTII

enhanceable

oxt

(Ueyama et al., 2008)

External Data

Linkouts

DroID - A comprehensive database of gene and protein interactions.

FBgn0015360

Pathways

Signaling Pathways (FlyBase)

Metabolic Pathways

FlyCyc Pathways - Pathways from a BioCyc PGDB for Dmel

KEGG Metabolic Pathways - A collection of manually drawn metabolic pathway maps representing knowledge of molecular interaction, reaction and relation networks.

Reactome Metabolic Pathways - An open-source, open access, manually curated and peer-reviewed metabolic pathway database.

A tetrasaccharide linker sequence is required for GAG synthesis

External Data

Linkouts

KEGG Pathways - A collection of manually drawn pathway maps representing knowledge of molecular interaction, reaction and relation networks.

Reactome - An open-source, open access, manually curated and peer-reviewed pathway database.

A tetrasaccharide linker sequence is required for GAG synthesis

SignaLink - A signaling pathway resource with multi-layered regulatory networks.

Q7KVA1

Genomic Location and Detailed Mapping Data

Chromosome (arm)

Recombination map

3-2

Cytogenetic map

62D4-62D4

Sequence location

3L:2,258,839..2,262,664 [-]

FlyBase Computed Cytological Location

Cytogenetic map

Evidence for location

62D4-62D4

Limits computationally determined from genome sequence between P{PZ}sls^rL182 and P{PZ}Spn⁰⁶⁹¹¹

Experimentally Determined Cytological Location

Cytogenetic map

Notes

References

Experimentally Determined Recombination Data

Location

3-2

(FlyBase, 2016)

3-4.2

(Comeron et al., 2012)

Left of (cM)

Right of (cM)

Notes

Stocks and Reagents

Stocks (8)

Aberrations including deletions of this gene Aberrations including duplications of this gene

Bloomington

55242

y¹ v¹; P{TRiP.HMC02377}attP2

27475

y¹ w^*; P{EP}oxt^G4946

38985

y¹ v¹; P{TRiP.HMS01901}attP40

85123

w¹¹¹⁸; PBac{RB}oxt^e01393/TM6B, Tb¹

76392

y¹ sc^* v¹ sev²¹; P{TKO.GS00561}attP40

NIG-Fly

HMS01901

y¹ v¹; P{TRiP.HMS01901}attP40/CyO

VDRC

v7442

w¹¹¹⁸; P{GD2261}v7442

v7443

w¹¹¹⁸; P{GD2261}v7443

Genomic Clones (14)

Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete

cDNA Clones (29)

Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see JBrowse for alignment of the cDNAs and ESTs to the gene model.

cDNA clones, fully sequenced

BDGP DGC clones

LD43716

Other clones

Drosophila Genomics Resource Center cDNA clones

For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.

FBgn0015360

cDNA Clones, End Sequenced (ESTs)

BDGP DGC clones

Other clones

RNAi and Array Information

Linkouts

DRSC - Results frm RNAi screens

FBgn0015360

Antibody Information

Laboratory Generated Antibodies

Commercially Available Antibodies

Cell Line Information

Publicly Available Cell Lines

Other Stable Cell Lines

Other Comments

Relationship to Other Genes

Source for database merge of

Source for merge of: CG17771 CG17772

(FlyBase Genome Annotators, 2002-2003, Whitfield, 2000.5.4)

Additional comments

Annotations CG17771 and CG17772 merged as CG32300 in release 3 of the genome annotation.

(FlyBase Genome Annotators, 2002-2003)

Source for identity of oxt CG17771 was sequence comparison ( date:020416 ).

(FlyBase, 1996-)

Nomenclature History

Source for database identify of

Source for identity of: oxt CG17771

(FlyBase, 1996-)

Nomenclature comments

Etymology

Synonyms and Secondary IDs (14)

Reported As

Symbol Synonym

CG17771

(Gaziova et al., 2004, Wilson, 2004, Wilson, 2002, Wilson, 2001.3.22, Whitfield, 2000.5.4)

CG17772

(Yamamoto-Hino et al., 2015, Gaziova et al., 2004, Whitfield, 2000.5.4)

CG32300

(Ibaraki et al., 2021, Yamamoto-Hino et al., 2015, Ni et al., 2010.12.1)

OXT

(Voglmeir et al., 2007)

Oxt

(Matsumoto et al., 2016, Yamamoto-Hino et al., 2015)

anon-i2

dOXT

(Ueyama et al., 2008, Goda et al., 2006)

dXylT

(Yamamoto-Hino et al., 2015, Nishihara, 2010)

oxt

(Ibaraki et al., 2021, Bolus et al., 2020, Transgenic RNAi Project members, 2017-, Bartok et al., 2015, Shulman et al., 2014, Wasbrough et al., 2010, Bornemann et al., 2008, Brunner et al., 2006)

Name Synonyms

Drosophila peptide O-xylosyltransferase

(Brunner et al., 2006)

O-xylosyltransferase

(Matsumoto et al., 2016)

Peptide-O-xylosyl-transferase

(Yamamoto-Hino et al., 2015)

Peptide-o-xylosyltransferase

(Bornemann et al., 2008)

peptide O-xylosyltransferase

Secondary FlyBase IDs

FBgn0035322
FBgn0052300

Datasets (0)

Study focus (0)

Experimental Role

Project

Project Type

Title

Study result (0)

Result

Result Type

Title

External Crossreferences and Linkouts ( 50 )

Sequence Crossreferences

NCBI Gene - Gene integrates information from a wide range of species. A record may include nomenclature, Reference Sequences (RefSeqs), maps, pathways, variations, phenotypes, and links to genome-, phenotype-, and locus-specific resources worldwide.

38288

GenBank Nucleotide - A collection of sequences from several sources, including GenBank, RefSeq, TPA, and PDB.

GenBank Protein - A collection of sequences from several sources, including translations from annotated coding regions in GenBank, RefSeq and TPA, as well as records from SwissProt, PIR, PRF, and PDB.

RefSeq - A comprehensive, integrated, non-redundant, well-annotated set of reference sequences including genomic, transcript, and protein.

UniProt/GCRP - The gene-centric reference proteome (GCRP) provides a 1:1 mapping between genes and UniProt accessions in which a single 'canonical' isoform represents the product(s) of each protein-coding gene.

Q7KVA1

UniProt/Swiss-Prot - Manually annotated and reviewed records of protein sequence and functional information

Q7KVA1

Other crossreferences

AlphaFold DB - AlphaFold provides open access to protein structure predictions for the human proteome and other key proteins of interest, to accelerate scientific research.

Q7KVA1

BDGP expression data - Patterns of gene expression in Drosophila embryogenesis

FBgn0015360

DRscDB - A single-cell RNA-seq resource for data mining and data comparison across species

38288/tissue=All

EMBL-EBI Single Cell Expression Atlas - Single cell expression across species

FBgn0015360

FlyAtlas2 - A Drosophila melanogaster expression atlas with RNA-Seq, miRNA-Seq and sex-specific data

FBgn0015360

FlyMine - An integrated database for Drosophila genomics

FBgn0015360

InterPro - A database of protein families, domains and functional sites

KEGG Genes - Molecular building blocks of life in the genomic space.

dme:Dmel_CG32300

MARRVEL_MODEL - MARRVEL (model organism gene)

38288

Linkouts

Drosophila Genomics Resource Center - Drosophila Genomics Resource Center (DGRC) cDNA clones

FBgn0015360

DroID - A comprehensive database of gene and protein interactions.

FBgn0015360

DRSC - Results frm RNAi screens

FBgn0015360

Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.

oxt_1

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

FBgn0015360

FlyCyc Genes - Genes from a BioCyc PGDB for Dmel

FBGN0015360

FlyCyc Pathways - Pathways from a BioCyc PGDB for Dmel

Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns

CG32300

Flygut - An atlas of the Drosophila adult midgut

FBgn0015360

FlyMet - A comprehensive tissue-specific metabolomics resource for Drosophila.

FBgn0015360

iBeetle-Base - RNAi phenotypes in the red flour beetle (Tribolium castaneum)

TC002371

KEGG Metabolic Pathways - A collection of manually drawn metabolic pathway maps representing knowledge of molecular interaction, reaction and relation networks.

KEGG Pathways - A collection of manually drawn pathway maps representing knowledge of molecular interaction, reaction and relation networks.

Reactome - An open-source, open access, manually curated and peer-reviewed pathway database.

A tetrasaccharide linker sequence is required for GAG synthesis

Reactome Metabolic Pathways - An open-source, open access, manually curated and peer-reviewed metabolic pathway database.

A tetrasaccharide linker sequence is required for GAG synthesis

SignaLink - A signaling pathway resource with multi-layered regulatory networks.

Q7KVA1

References (60)

The following external sites may use different assemblies or annotations than FlyBase.

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