LCP-3
Please see the JBrowse view of Dmel\Lcp3 for information on other features
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AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Some regions with low pLDDT may be unstructured in isolation.
Apparent introns not annotated: probable artifacts due to repetitive sequence.
Low-frequency RNA-Seq exon junction(s) not annotated.
Gene model reviewed during 5.46
0.5-0.6 (northern blot)
112 (aa)
9 (kD observed)
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\Lcp3 using the Feature Mapper tool.
The testis specificity index was calculated from modENCODE tissue expression data by Vedelek et al., 2018 to indicate the degree of testis enrichment compared to other tissues. Scores range from -2.52 (underrepresented) to 5.2 (very high testis bias).
Lcp3 is expressed in the integument of late third instar larvae.
JBrowse - Visual display of RNA-Seq signals
View Dmel\Lcp3 in JBrowse2-58
2-57.6
Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see JBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
In a sample of 79 genes with multiple introns, 33 showed significant heterogeneity in G+C content among introns of the same gene and significant positive correspondence between the intron and the third codon position G+C content within genes. These results are consistent with selection adding against preferred codons at the start of genes.
One of a series of genes encoding electrophoretically separable proteins extractable from the cuticles of third instar larvae, but not other stages. Four immunologically related proteins are encoded by a cluster of genes on 2R and another cluster of three unrelated to the preceding four, but related to each other, located on 3L. Lcp3 encodes larval cuticle protein CP3 (alternatively L3CP3); molecular weight 9kD. Has a 15-residue signal peptide.
Source for identity of: Lcp3 CG2043