FB2024_03 , released June 25, 2024
Gene Group - Macromolecular Complex: SODIUM LEAK CHANNEL COMPLEX
Open Close
General Information
Name
SODIUM LEAK CHANNEL COMPLEX
Species
D. melanogaster
Symbol
NALCN
FlyBase ID
FBgg0001886
Date last reviewed
2024-02-22
Number of members
4
Description
Description
The sodium leak channel is a non-selective, constitutively active monovalent cation channel complex that conducts depolarizing sodium ion leak currents in electrically excitable cells to regulate resting membrane potential. The complex consists of the channel-forming na and accessory subunits, which are required for reconstituting a functional channel. (Adapted from PMID:37615954.)
Notes on Group
Source Material
The SODIUM LEAK CHANNEL COMPLEX Gene Group has been compiled using the following publication(s): Monteil et al., 2024, Ghezzi et al., 2014, Lear et al., 2013, Humphrey et al., 2007, and Nash et al., 2002 .
Key Gene Ontology (GO) terms
Molecular Function
monoatomic cation channel activity
leak channel activity
Biological Process
monoatomic cation transport
Cellular Component
cation channel complex
plasma membrane
Related Gene Groups
Parent group(s)
NON-SELECTIVE CATION CHANNEL SUBUNITS
Members (4)
For all members:
GO ribbon stack
 molecular functionbiological processcellular component
Gene Symbol
Gene Name
Also Known As
Source Material for Membership
Mid1
Mid1
Nlf-1
(Monteil et al., 2024, Ghezzi et al., 2014)
na
narrow abdomen
har38, har, NALCN, har85
(Monteil et al., 2024, Ghezzi et al., 2014, Lear et al., 2013, Humphrey et al., 2007, Nash et al., 2002)
unc79
uncoordinated 79
dunc79
(Monteil et al., 2024, Ghezzi et al., 2014, Lear et al., 2013, Humphrey et al., 2007)
unc80
uncoordinated 80
(Monteil et al., 2024, Ghezzi et al., 2014, Lear et al., 2013)
External Data
Equivalent Group(s)
Other resource(s)
Synonyms and Secondary IDs
Synonym(s)
NALCN
Narrow abdomen sodium channel complex
SODIUM LEAK CHANNEL COMPLEX
Na+ leak channel, non-selective
Secondary FlyBase ID(s)
References (6)