FB2024_03 , released June 25, 2024
Gene Group - Macromolecular Complex: MITOCHONDRIAL COMPLEX II (SUCCINATE DEHYDROGENASE) - TESTIS-SPECIFIC VARIANT
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General Information
Name
MITOCHONDRIAL COMPLEX II (SUCCINATE DEHYDROGENASE) - TESTIS-SPECIFIC VARIANT
Species
D. melanogaster
Symbol
MCII-T
FlyBase ID
FBgg0001848
Date last reviewed
2023-04-03
Number of members
4
Description
Description
Mitochondrial complex II/Succinate Dehydrogenase is a heterotetrameric protein complex anchored to the inner mitochondrial membrane via two integral membrane subunits. It functions both in the tricarboxylic acid (TCA) cycle and the electron transport chain (ETC) by catalysing the oxidation of succinate to fumarate and then, via electron transfer, reducing ubiquinone to ubiquinol. (Adapted from PMID:24954416.)
Notes on Group
Source Material
The MITOCHONDRIAL COMPLEX II (SUCCINATE DEHYDROGENASE) - TESTIS-SPECIFIC VARIANT Gene Group has been compiled using the following publication(s): Vedelek et al., 2018 and Tripoli et al., 2005 .
Key Gene Ontology (GO) terms
Molecular Function
succinate dehydrogenase (quinone) activity
Biological Process
mitochondrial electron transport, succinate to ubiquinone
tricarboxylic acid cycle
Cellular Component
mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)
Enzymatic activity
Enzyme name (EC)
succinate dehydrogenase (1.3.5.1)
Related Gene Groups
Parent group(s)
MITOCHONDRIAL OXPHOS COMPLEX VARIANTS
Other related group(s)
MITOCHONDRIAL COMPLEX II (SUCCINATE DEHYDROGENASE) SUBUNITS
Members (4)
For all members:
GO ribbon stack
 molecular functionbiological processcellular component
Gene Symbol
Gene Name
Also Known As
Source Material for Membership
SdhAL
Succinate dehydrogenase, subunit A (flavoprotein)-like
(Tripoli et al., 2005)
SdhBL
Succinate dehydrogenase, subunit B (iron-sulfur)-like
(Tripoli et al., 2005)
SdhCL
Succinate dehydrogenase, subunit C-like
(Vedelek et al., 2018)
SdhD
Succinate dehydrogenase, subunit D
(Tripoli et al., 2005)
External Data
Equivalent Group(s)
Other resource(s)
Synonyms and Secondary IDs
Synonym(s)
MCII-T
SDH
MITOCHONDRIAL COMPLEX II (SUCCINATE DEHYDROGENASE) - TESTIS-SPECIFIC VARIANT
Succinate dehydrogenase
Secondary FlyBase ID(s)
References (3)