FB2024_04 , released June 25, 2024
Gene Group - Macromolecular Complex: 26S PROTEASOME - TESTIS-SPECIFIC VARIANT
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General Information
Name
26S PROTEASOME - TESTIS-SPECIFIC VARIANT
Species
D. melanogaster
Symbol
PSM26S-T
FlyBase ID
FBgg0001838
Date last reviewed
2023-04-03
Number of members
38
Description
Description
The 26S proteasome degrades polyubiquitinated proteins in the cytoplasm and nucleus. It is formed from a cylindrical catalytic core 20S proteasome capped at each end by a regulatory 19S particle. The 19S regulatory particle recognizes, unfolds, and translocates ubiquitinated proteins into the catalytic core particle in an ATP-dependent manner. (Adapted from FBrf0215459).
Notes on Group
Source Material
The 26S PROTEASOME - TESTIS-SPECIFIC VARIANT Gene Group has been compiled using the following publication(s): Crosby et al., 2013.1.30 and Belote and Zhong, 2009 .
Key Gene Ontology (GO) terms
Molecular Function
threonine-type endopeptidase activity
Biological Process
proteasome-mediated ubiquitin-dependent protein catabolic process
Cellular Component
proteasome complex
Enzymatic activity
Enzyme name (EC)
3.4.25.-
Related Gene Groups
Parent group(s)
PROTEASOME 26S COMPLEX VARIANTS
Members (38)
For all members:
GO ribbon stack
 molecular functionbiological processcellular component
Gene Symbol
Gene Name
Also Known As
Source Material for Membership
Prosα1
Proteasome α1 subunit
α1, Prosalpha6, Proteasome α6 subunit, Proteasome alpha6 subunit, alpha1
(Belote and Zhong, 2009)
Prosα1R
Proteasome α1 subunit-related
(Crosby et al., 2013.1.30)
Prosα2
Proteasome α2 subunit
Pros25, α2, Proteasome 25kD subunit, PROS Dm25, 20S-α
(Belote and Zhong, 2009)
Prosα3T
Proteasome α3 subunit, Testis-specific
(Belote and Zhong, 2009)
Prosα4T1
Proteasome α4 subunit, Testis-specific 1
Pros28.1A, α4t1_dm
(Belote and Zhong, 2009)
Prosα4T2
Proteasome α4 subunit, Testis-specific 2
Pros28.1B, α4t2_dm
(Belote and Zhong, 2009)
Prosα5
Proteasome α5 subunit
ProsMA5, α5, PSMA5, alpha5
(Belote and Zhong, 2009)
Prosα6T
Proteasome α6 subunit, Testis-specific
(Belote and Zhong, 2009)
Prosα7
Proteasome α7 subunit
α7, CPα7, alpha7
(Belote and Zhong, 2009)
Prosβ1
Proteasome β1 subunit
l(2)05070, β1, lethal (2) 05070
(Belote and Zhong, 2009)
Prosβ2R1
Proteasome β2 subunit-related 1
(Belote and Zhong, 2009)
Prosβ2R2
Proteasome β2 subunit-related 2
(Belote and Zhong, 2009)
Prosβ3
Proteasome β3 subunit
β3
(Belote and Zhong, 2009)
Prosβ4R1
Proteasome β4 subunit-related 1
(Belote and Zhong, 2009)
Prosβ4R2
Proteasome β4 subunit-related 2
(Belote and Zhong, 2009)
Prosβ5R1
Proteasome β5 subunit-related 1
Prosβ5R
(Belote and Zhong, 2009)
Prosβ5R2
Proteasome β5 subunit-related 2
(Belote and Zhong, 2009)
Prosβ6
Proteasome β6 subunit
Pros26, DTS5, l(3)73Ai, β6, DTS-5
(Belote and Zhong, 2009)
Prosβ7
Proteasome β7 subunit
Prosβ4, β7
(Belote and Zhong, 2009)
Rpn1
Regulatory particle non-ATPase 1
p97
(Belote and Zhong, 2009)
Rpn2
Regulatory particle non-ATPase 2
p110
(Belote and Zhong, 2009)
Rpn3
Regulatory particle non-ATPase 3
Dox-A2, p58, l(2)37Bf, Diphenol oxidase A2, DoxA2
(Belote and Zhong, 2009)
Rpn5
Regulatory particle non-ATPase 5
p55
(Belote and Zhong, 2009)
Rpn6
Regulatory particle non-ATPase 6
l(2)k00103, p42B, Pros44.5
(Belote and Zhong, 2009)
Rpn7
Regulatory particle non-ATPase 7
p42A
(Belote and Zhong, 2009)
Rpn8
Regulatory particle non-ATPase 8
Mov34, p39B, l(2)k08003
(Belote and Zhong, 2009)
Rpn9
Regulatory particle non-ATPase 9
p39A, Rpn4
(Belote and Zhong, 2009)
Rpn10
Regulatory particle non-ATPase 10
p54, Pros54, S5a
(Belote and Zhong, 2009)
Rpn11
Regulatory particle non-ATPase 11
p37B, DmS13, S13, 37B
(Belote and Zhong, 2009)
Rpn12R
Regulatory particle non-ATPase 12-related
(Belote and Zhong, 2009)
Rpn13R
Regulatory particle non-ATPase 13-related
(Belote and Zhong, 2009)
Rpt1
Regulatory particle triple-A ATPase 1
p48B, l(2)05643, l(2)43Ed, AAA ATPase
(Belote and Zhong, 2009)
Rpt2
Regulatory particle triple-A ATPase 2
Pros26.4, S4, p56, dRpt2
(Belote and Zhong, 2009)
Rpt3R
Regulatory particle triple-A ATPase 3-related
(Belote and Zhong, 2009)
Rpt4R
Regulatory particle triple-A ATPase 4-related
(Belote and Zhong, 2009)
Rpt5
Regulatory particle triple-A ATPase 5
Tbp-1, p50, l(3)04210, Tat-binding protein-1, Pros26S-RS6A
(Belote and Zhong, 2009)
Rpt6R
Regulatory particle triple-A ATPase 6-related
(Belote and Zhong, 2009)
Uch-L5R
Uch-L5-related
(Belote and Zhong, 2009)
External Data
Equivalent Group(s)
Other resource(s)
Synonyms and Secondary IDs
Synonym(s)
PSM26S-T
26S PROTEASOME - TESTIS-SPECIFIC VARIANT
Secondary FlyBase ID(s)
References (3)