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FB2024_03
,
released June 25, 2024
Tools
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Query by symbols/IDs
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FB2024_03
,
released June 25, 2024
Gene Group: PROTEIN PHOSPHATASES
J2G
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General Information
Name
PROTEIN PHOSPHATASES
Species
D. melanogaster
Symbol
PPASE
FlyBase ID
FBgg0000264
Date last reviewed
2015-06-08
Number of members
87
Description
Description
Protein phosphatases are enzymes that catalyse the hydrolysis of a phosphate group from a protein. The protein phosphatase families are structurally and mechanistically distinct. (Adapted from
FBrf0129980
).
Notes on Group
Source Material
The PROTEIN PHOSPHATASES Gene Group has been compiled using the following publication(s):
Lee et al., 2020
,
Hatzihristidis et al., 2015
,
Fuhrmann et al., 2013
,
Cao et al., 2011
,
Miskei et al., 2011
,
Zhang et al., 2011
,
Imai et al., 2010
,
Pan and Zhang, 2009
,
Hudson et al., 2007
,
Burroughs et al., 2006
,
Andersen et al., 2004
,
Morrison et al., 2000
, and
Walchli et al., 2000
.
Key Gene Ontology (GO) terms
Molecular Function
phosphoprotein phosphatase activity
Biological Process
protein dephosphorylation
Cellular Component
Related Gene Groups
Parent group(s)
PHOSPHATASES
Component group(s)
HAD FAMILY PROTEIN PHOSPHATASES
PROTEIN ARGININE PHOSPHATASES
PROTEIN HISTIDINE PHOSPHATASES
PROTEIN SERINE/THREONINE PHOSPHATASES
PROTEIN TYROSINE PHOSPHATASES
Other related group(s)
PROTEIN KINASES
Members (87)
For all members:
View Orthologs
Export to HitList
Export to Batch Download
GO ribbon stack
molecular function
biological process
cellular component
×
body
Unable to display GO ribbon stack for gene groups with more than 100 members.
CDC25 FAMILY PROTEIN PHOSPHATASES
Gene Symbol
Gene Name
Also Known As
Source Material for Membership
stg
string
cdc25, cdc25
string
, l(3)01235, string/cdc25, EP1213
(
Hatzihristidis et al., 2015
,
Morrison et al., 2000
,
Walchli et al., 2000
)
twe
twine
Cdc25, twn, l(2)35Fh, mat(2)syn
HB5
, BG:DS02740.1
(
Hatzihristidis et al., 2015
,
Morrison et al., 2000
)
CTD FAMILY PROTEIN SERINE/THREONINE PHOSPHATASES
Gene Symbol
Gene Name
Also Known As
Source Material for Membership
CG8584
(
Burroughs et al., 2006
)
CG12078
(
Burroughs et al., 2006
)
Dd
Dullard
l(1)G0269, ddd
(
Burroughs et al., 2006
)
Fcp1
TFIIF-interacting CTD phosphatase
(
Burroughs et al., 2006
)
hzg
herzog
(
Burroughs et al., 2006
)
ttm2
tiny tim 2
(
Burroughs et al., 2006
)
ttm3
tiny tim 3
(
Pan and Zhang, 2009
)
ttm50
tiny tim 50
EG:95B7.3, Gp99
(
Burroughs et al., 2006
)
Ublcp1
Ubiquitin-like domain-containing C-terminal domain phosphatase 1
BcDNA:LD21504
(
Burroughs et al., 2006
)
CYTOSOLIC PROTEIN TYROSINE PHOSPHATASES
Gene Symbol
Gene Name
Also Known As
Source Material for Membership
CG14297
(
Hatzihristidis et al., 2015
,
Morrison et al., 2000
)
csw
corkscrew
E(sev)1A, l(1)2Db, l(1)csw, EG:BACN25G24.2, SHP-2
(
Hatzihristidis et al., 2015
,
Andersen et al., 2004
,
Morrison et al., 2000
,
Walchli et al., 2000
)
primo-1
primo-1
(
Lee et al., 2020
,
Morrison et al., 2000
)
primo-2
primo-2
(
Morrison et al., 2000
)
Ptp61F
Protein tyrosine phosphatase 61F
DPTP61F, protein tyrosine phosphatase
(
Hatzihristidis et al., 2015
,
Andersen et al., 2004
,
Morrison et al., 2000
,
Walchli et al., 2000
)
PTP-ER
Protein tyrosine phosphatase-ERK/Enhancer of Ras1
ER2-5
(
Hatzihristidis et al., 2015
,
Andersen et al., 2004
,
Morrison et al., 2000
)
Ptpmeg
Protein tyrosine phosphatase Meg
Meg
(
Hatzihristidis et al., 2015
,
Andersen et al., 2004
,
Morrison et al., 2000
,
Walchli et al., 2000
)
Ptpmeg2
Protein tyrosine phosphatase Meg2
l(1)G0232
(
Hatzihristidis et al., 2015
,
Andersen et al., 2004
,
Morrison et al., 2000
,
Walchli et al., 2000
)
DUAL SPECIFICITY PROTEIN PHOSPHATASES
Gene Symbol
Gene Name
Also Known As
Source Material for Membership
Cdc14
Cell division cycle 14
(
Hatzihristidis et al., 2015
,
Morrison et al., 2000
,
Walchli et al., 2000
)
CG3632
(
Hatzihristidis et al., 2015
,
Morrison et al., 2000
)
CG7378
MKP-like
(
Hatzihristidis et al., 2015
,
Morrison et al., 2000
)
CG10089
(
Hatzihristidis et al., 2015
,
Morrison et al., 2000
)
CG13197
(
Hatzihristidis et al., 2015
,
Morrison et al., 2000
)
CG15528
(
Hatzihristidis et al., 2015
,
Morrison et al., 2000
)
EDTP
Egg-derived tyrosine phosphatase
(
Hatzihristidis et al., 2015
)
Mkp
MAP kinase-specific phosphatase
DMKP
(
Hatzihristidis et al., 2015
)
Mkp3
Mitogen-activated protein kinase phosphatase 3
DMKP-3, MAP Kinase Phosphatase 3
(
Hatzihristidis et al., 2015
,
Morrison et al., 2000
,
Walchli et al., 2000
)
MKP-4
MAPK Phosphatase 4
MAPK
(
Hatzihristidis et al., 2015
,
Morrison et al., 2000
)
mtm
myotubularin
(
Hatzihristidis et al., 2015
,
Morrison et al., 2000
,
Walchli et al., 2000
)
Mtmr6
Myotubularin related protein 6
BcDNA:GH04637
(
Hatzihristidis et al., 2015
,
Morrison et al., 2000
,
Walchli et al., 2000
)
PRL-1
PRL-1 phosphatase
PRL, BG:DS07473.3
(
Hatzihristidis et al., 2015
,
Morrison et al., 2000
,
Walchli et al., 2000
)
Pten
Phosphatase and tensin homolog
dPTEN
(
Hatzihristidis et al., 2015
,
Morrison et al., 2000
,
Walchli et al., 2000
)
PTPMT1
Protein tyrosine phosphatase, mitochondrial 1
Plip
(
Hatzihristidis et al., 2015
,
Morrison et al., 2000
)
puc
puckered
hrt, l(3)84Eh, vco, hearty
(
Hatzihristidis et al., 2015
,
Morrison et al., 2000
,
Walchli et al., 2000
)
ssh
slingshot
l(3)01207, MKP, Mkph
(
Hatzihristidis et al., 2015
,
Morrison et al., 2000
)
EYA FAMILY PROTEIN TYROSINE PHOSPHATASES
Gene Symbol
Gene Name
Also Known As
Source Material for Membership
eya
eyes absent
cli, clift, ey-2
(
Hatzihristidis et al., 2015
,
Burroughs et al., 2006
)
PPM FAMILY PROTEIN SERINE/THREONINE PHOSPHATASES
Gene Symbol
Gene Name
Also Known As
Source Material for Membership
alph
alphabet
SK3-1, pp2c99B
(
Morrison et al., 2000
)
CG7115
BcDNA:LD21794
(
Morrison et al., 2000
)
CG10376
(
Morrison et al., 2000
)
CG10417
(
Morrison et al., 2000
)
CG12091
(
Hudson et al., 2007
)
CG15035
(
Hudson et al., 2007
)
CG17598
(
Morrison et al., 2000
)
CG17746
(
Morrison et al., 2000
)
fig
fos intronic gene
(
Hudson et al., 2007
)
Mppe
Metallophosphoesterase
dmppe
(
Cao et al., 2011
)
Nil
Nilkantha
(
Morrison et al., 2000
)
Pdp
Pyruvate dehydrogenase phosphatase
(
Morrison et al., 2000
)
Phlpp
PH domain leucine-rich repeat protein phosphatase
(
Morrison et al., 2000
)
Pp2C1
Protein phosphatase 2C
dpp2c1, PP2C
(
Morrison et al., 2000
)
Ppm1
Ppm1
(
Morrison et al., 2000
)
PPP FAMILY PROTEIN SERINE/THREONINE PHOSPHATASES
Gene Symbol
Gene Name
Also Known As
Source Material for Membership
CanA1
Calcineurin A1
calcineurin, CaN, PP2B 21EF
(
Miskei et al., 2011
,
Morrison et al., 2000
)
CanA-14F
Calcineurin A at 14F
MRE12, Calcineurin
(
Miskei et al., 2011
,
Morrison et al., 2000
)
CG11597
PP4-like
(
Miskei et al., 2011
,
Morrison et al., 2000
)
flw
flapwing
PP1β9C, PP1, PP1β, PP1c, PP1 9C
(
Miskei et al., 2011
,
Morrison et al., 2000
)
mts
microtubule star
PP2A, PP2A-C, PP2Ac, PP2A catalytic subunit, protein phosphatase 2A
(
Miskei et al., 2011
,
Morrison et al., 2000
)
Pp1-13C
Protein phosphatase 1 at 13C
PP1α13C, PP1, PP1 13C, PP1c, 13C
(
Miskei et al., 2011
,
Morrison et al., 2000
)
Pp1-87B
Protein phosphatase 1 at 87B
Su(var)3-6, PP1α87B, PP1, Su-var(3)6, PP1 87B
(
Miskei et al., 2011
,
Morrison et al., 2000
)
Pp1α-96A
Protein phosphatase 1α at 96A
PP1α96A, Pp1-96A, PP1, PP1 96A, PP1c
(
Miskei et al., 2011
,
Morrison et al., 2000
)
Pp1-Y1
Protein phosphatase 1, Y-linked 1
(
Miskei et al., 2011
)
Pp1-Y2
Protein phosphatase 1, Y-linked 2
Pp1Y2
(
Miskei et al., 2011
)
Pp2B-14D
Protein phosphatase 2B at 14D
CnnA14D, canA, calcineurin, PP2B 14D, CaN
(
Miskei et al., 2011
,
Morrison et al., 2000
)
Pp4-19C
Protein phosphatase 19C
PP4, PP4c
(
Miskei et al., 2011
,
Morrison et al., 2000
)
PpD3
Protein phosphatase D3
PP5, Pp5-85E
(
Miskei et al., 2011
,
Morrison et al., 2000
)
PpD5
Protein phosphatase D5
(
Miskei et al., 2011
,
Morrison et al., 2000
)
PpD6
Protein phosphatase D6
PP1-like
(
Miskei et al., 2011
,
Morrison et al., 2000
)
PpN58A
Protein phosphatase N at 58A
PPN 58A
(
Miskei et al., 2011
,
Morrison et al., 2000
)
PpV
Protein phosphatase V
(
Miskei et al., 2011
,
Morrison et al., 2000
)
PpY-55A
Protein phosphatase Y at 55A
PPY, PPY 55A
(
Miskei et al., 2011
,
Morrison et al., 2000
)
rdgC
retinal degeneration C
(
Miskei et al., 2011
,
Morrison et al., 2000
)
PROTEIN ARGININE PHOSPHATASES
Gene Symbol
Gene Name
Also Known As
Source Material for Membership
Argp
Arginine phosphatase
(
Lee et al., 2020
,
Fuhrmann et al., 2013
)
PROTEIN HISTIDINE PHOSPHATASES
Gene Symbol
Gene Name
Also Known As
Source Material for Membership
CG18662
(
FlyBase, 2017-
)
janA
janus A
janus, Y
(
FlyBase, 2017-
)
janB
janus B
janus
(
FlyBase, 2017-
)
ocn
ocnus
BcDNA:GH02250
(
FlyBase, 2017-
)
RECEPTOR PROTEIN TYROSINE PHOSPHATASES
Gene Symbol
Gene Name
Also Known As
Source Material for Membership
CG42327
(
Hatzihristidis et al., 2015
,
Andersen et al., 2004
,
Morrison et al., 2000
)
Lar
Leukocyte-antigen-related-like
Dlar, bypass
(
Hatzihristidis et al., 2015
,
Andersen et al., 2004
,
Morrison et al., 2000
)
Ptp4E
Protein tyrosine phosphatase 4E
DPTP4E
(
Hatzihristidis et al., 2015
,
Andersen et al., 2004
,
Morrison et al., 2000
)
Ptp10D
Protein tyrosine phosphatase 10D
DPTP10D
(
Hatzihristidis et al., 2015
,
Andersen et al., 2004
,
Morrison et al., 2000
,
Walchli et al., 2000
)
Ptp52F
Protein tyrosine phosphatase 52F
DPTP52F
(
Hatzihristidis et al., 2015
,
Andersen et al., 2004
,
Morrison et al., 2000
)
Ptp69D
Protein tyrosine phosphatase 69D
DPTP69D, DPTP
(
Hatzihristidis et al., 2015
,
Andersen et al., 2004
,
Morrison et al., 2000
)
Ptp99A
Protein tyrosine phosphatase 99A
DPTP99A
(
Hatzihristidis et al., 2015
,
Andersen et al., 2004
,
Morrison et al., 2000
,
Walchli et al., 2000
)
UNCLASSIFIED PROTEIN SERINE/THREONINE PHOSPHATASES
Gene Symbol
Gene Name
Also Known As
Source Material for Membership
CG34183
(
FlyBase, 2017-
)
Pgam5
Phosphoglycerate mutase 5
EG:63B12.4, dPGAM5
(
Imai et al., 2010
)
Pgam5-2
Phosphoglycerate mutase 5-2
(
Imai et al., 2010
)
Ssu72
Ssu72 CTD phosphatase
(
Zhang et al., 2011
)
External Data
Equivalent Group(s)
Human Protein Phosphatases (HGNC)
Other resource(s)
Synonyms and Secondary IDs
Synonym(s)
PPASE
PROTEIN PHOSPHATASES
Secondary FlyBase ID(s)
References (15)
Report Sections
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Close
General Information
Description
Members
External Data
Synonyms and Secondary IDs
References