FB2024_03 , released June 25, 2024
Gene Group: RECEPTOR PROTEIN TYROSINE PHOSPHATASES
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General Information
Name
RECEPTOR PROTEIN TYROSINE PHOSPHATASES
Species
D. melanogaster
Symbol
RPTP
FlyBase ID
FBgg0000257
Date last reviewed
2022-11-01
Number of members
7
Description
Description
Receptor Protein Tyrosine Phosphatases possess a single transmembrane domain and are localized to the plasma membrane. The Protein Tyrosine Phosphatases are defined by the active-site signature motif Cys-X5-Arg. (Adapted from FBrf0129980 and PMID:17057753).
Notes on Group

IA-2 is predicted to encode a pseudophosphatase in FBrf0227974 and is therefore omitted from this group.

Source Material
The RECEPTOR PROTEIN TYROSINE PHOSPHATASES Gene Group has been compiled using the following publication(s): Hatzihristidis et al., 2015, Andersen et al., 2004, Morrison et al., 2000, and Walchli et al., 2000 .
Key Gene Ontology (GO) terms
Molecular Function
transmembrane receptor protein tyrosine phosphatase activity
Biological Process
protein dephosphorylation
Cellular Component
plasma membrane
Enzymatic activity
Enzyme name (EC)
protein-tyrosine-phosphatase (3.1.3.48)
Related Gene Groups
Parent group(s)
PROTEIN TYROSINE PHOSPHATASES
TRANSMEMBRANE RECEPTORS
Members (7)
For all members:
GO ribbon stack
 molecular functionbiological processcellular component
Gene Symbol
Gene Name
Also Known As
Source Material for Membership
CG42327
(Hatzihristidis et al., 2015, Andersen et al., 2004, Morrison et al., 2000)
Lar
Leukocyte-antigen-related-like
Dlar, bypass
(Hatzihristidis et al., 2015, Andersen et al., 2004, Morrison et al., 2000)
Ptp4E
Protein tyrosine phosphatase 4E
DPTP4E
(Hatzihristidis et al., 2015, Andersen et al., 2004, Morrison et al., 2000)
Ptp10D
Protein tyrosine phosphatase 10D
DPTP10D
(Hatzihristidis et al., 2015, Andersen et al., 2004, Morrison et al., 2000, Walchli et al., 2000)
Ptp52F
Protein tyrosine phosphatase 52F
DPTP52F
(Hatzihristidis et al., 2015, Andersen et al., 2004, Morrison et al., 2000)
Ptp69D
Protein tyrosine phosphatase 69D
DPTP69D, DPTP
(Hatzihristidis et al., 2015, Andersen et al., 2004, Morrison et al., 2000)
Ptp99A
Protein tyrosine phosphatase 99A
DPTP99A
(Hatzihristidis et al., 2015, Andersen et al., 2004, Morrison et al., 2000, Walchli et al., 2000)
External Data
Equivalent Group(s)
Other resource(s)
Synonyms and Secondary IDs
Synonym(s)
RPTP
RECEPTOR PROTEIN TYROSINE PHOSPHATASES
Classical protein tyrosine phosphatases
Transmembrane receptor-like PTPs
Receptor-like protein tyrosine phosphatases
RPTPs
PTPR
Secondary FlyBase ID(s)
References (5)