FB2024_03 , released June 25, 2024
Gene Group - Macromolecular Complex: COAT PROTEIN COMPLEX II
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General Information
Name
COAT PROTEIN COMPLEX II
Species
D. melanogaster
Symbol
COPII
FlyBase ID
FBgg0000116
Date last reviewed
Number of members
6
Description
Description
The Coat Protein Complex II (COPII) mediates protein transport from the ER to Golgi (anterograde transport). COPII recruitment is initiated by the activation of the small GTPase Sar1. Sar1 recruits a heterodimeric complex comprising of Sec23/24, which interacts with cargo and the outer cage - a heterotetramer composed of Sec13/31. (Adapted from PMID:18060556).
Notes on Group
Source Material
The COAT PROTEIN COMPLEX II Gene Group has been compiled using the following publication(s): Iyer et al., 2013 .
Key Gene Ontology (GO) terms
Molecular Function
Biological Process
endoplasmic reticulum to Golgi vesicle-mediated transport
Cellular Component
COPII vesicle coat
Related Gene Groups
Parent group(s)
INTRACELLULAR TRANSPORT COAT, SCAFFOLD AND ADAPTOR PROTEINS
Members (6)
For all members:
GO ribbon stack
 molecular functionbiological processcellular component
Gene Symbol
Gene Name
Also Known As
Source Material for Membership
Sar1
Secretion-associated Ras-related 1
l(3)05712, bro5
(Iyer et al., 2013)
Sec13
Secretory 13
l(3)01031
(Iyer et al., 2013)
Sec23
Secretory 23
dSec23p, dSec23, haunted, hau, COPII
(Iyer et al., 2013)
Sec24AB
Secretory 24AB
sec24
(Iyer et al., 2013)
Sec24CD
Secretory 24CD
gho, sten, stenosis, ghost, Sec24
(Iyer et al., 2013)
Sec31
Secretory 31
(Iyer et al., 2013)
External Data
Synonyms and Secondary IDs
Synonym(s)
COPII
COAT PROTEIN COMPLEX II
Secondary FlyBase ID(s)
References (2)