GGAs (Golgi-localizing, Gamma-adaptin ear domain homology, ARF-binding proteins) are monomeric clathrin adaptor proteins. They share homology with the C-terminal ear domain of the γ adaptin AP1 subunit. GGAs regulate clathrin-mediated the transport of proteins from the trans-Golgi network to endosomes and lysosomes through interactions with TGN-sorting receptors. (Adapted from PMID:10611976).
Notes on Group
The GGA gene group only has one member.
Source Material
The
GOLGI-LOCALIZING, GAMMA-ADAPTIN EAR DOMAIN HOMOLOGY, ARF-BINDING PROTEINS
Gene Group has been compiled using the following publication(s):
Boehm, 2001 and Boehm and Bonifacino, 2001
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