FlyBase Allele Report: Dmel\ena[Δ151]

General Information

Symbol

Dmel\ena^Δ151

Species

D. melanogaster

Name

FlyBase ID

FBal0359778

Feature type

allele

Associated gene

Dmel\ena

Associated Insertion(s)

Carried in Construct

Key Links

Genomic Maps

JBrowse

Allele class

amorphic allele - molecular evidence

Mutagen

CRISPR/Cas9

Nature of the Allele

Allele class

amorphic allele - molecular evidence

(Yaniv et al., 2020)

Mutagen

CRISPR/Cas9

(Yaniv et al., 2020)

Progenitor genotype

Cytology

Description

One nucleotide deletion located 151 bases downstream of the start site of isoforms B and F of ena.

(Yaniv et al., 2020)

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

deletion

2R:19,155,625..19,155,625 [+]

Comment:

A one nucleotide deletion at position 151 within the CDS of ena-RB and ena-RF.

(Meltzer and Schuldiner, 2020.6.25)

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal neuroanatomy | adult stage | somatic clone

(Yaniv et al., 2020)

Phenotype Manifest In

adult mushroom body gamma-lobe | somatic clone

(Yaniv et al., 2020)

axon | adult stage | somatic clone

(Yaniv et al., 2020)

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

NOT Enhanced by

Statement

Reference

ena^Δ151 has abnormal neuroanatomy | adult stage | somatic clone phenotype, non-enhanceable by DAAM^ΔORF/DAAM^ΔORF

(Yaniv et al., 2020)

Suppressed by

Statement

Reference

ena^Δ151 has abnormal neuroanatomy | somatic clone | adult stage phenotype, suppressible by Scer\GAL4^GMR71G10/chic^UAS.cCa

(Yaniv et al., 2020)

ena^Δ151 has abnormal neuroanatomy | somatic clone | adult stage phenotype, suppressible by DAAM^DADm.UAS/Scer\GAL4^GMR71G10

(Yaniv et al., 2020)

NOT suppressed by

Statement

Reference

ena^Δ151 has abnormal neuroanatomy | somatic clone | adult stage phenotype, non-suppressible by DAAM^ΔORF/DAAM^ΔORF

(Yaniv et al., 2020)

DAAM^ΔORF, ena^Δ151 has abnormal neuroanatomy | somatic clone | adult stage phenotype, non-suppressible by Scer\GAL4^GMR71G10/chic^UAS.cCa

(Yaniv et al., 2020)

Phenotype Manifest In

NOT Enhanced by

Statement

Reference

ena^Δ151 has adult mushroom body gamma-lobe | somatic clone phenotype, non-enhanceable by DAAM^ΔORF/DAAM^ΔORF

(Yaniv et al., 2020)

ena^Δ151 has axon | adult stage | somatic clone phenotype, non-enhanceable by DAAM^ΔORF/DAAM^ΔORF

(Yaniv et al., 2020)

Suppressed by

Statement

Reference

ena^Δ151 has adult mushroom body gamma-lobe | somatic clone phenotype, suppressible by Scer\GAL4^GMR71G10/chic^UAS.cCa

(Yaniv et al., 2020)

ena^Δ151 has axon | somatic clone | adult stage phenotype, suppressible by Scer\GAL4^GMR71G10/chic^UAS.cCa

(Yaniv et al., 2020)

ena^Δ151 has adult mushroom body gamma-lobe | somatic clone phenotype, suppressible by DAAM^DADm.UAS/Scer\GAL4^GMR71G10

(Yaniv et al., 2020)

ena^Δ151 has axon | somatic clone | adult stage phenotype, suppressible by DAAM^DADm.UAS/Scer\GAL4^GMR71G10

(Yaniv et al., 2020)

NOT suppressed by

Statement

Reference

ena^Δ151 has adult mushroom body gamma-lobe | somatic clone phenotype, non-suppressible by DAAM^ΔORF/DAAM^ΔORF

(Yaniv et al., 2020)

ena^Δ151 has axon | somatic clone | adult stage phenotype, non-suppressible by DAAM^ΔORF/DAAM^ΔORF

(Yaniv et al., 2020)

DAAM^ΔORF, ena^Δ151 has adult mushroom body gamma-lobe | somatic clone phenotype, non-suppressible by Scer\GAL4^GMR71G10/chic^UAS.cCa

(Yaniv et al., 2020)

DAAM^ΔORF, ena^Δ151 has axon | somatic clone | adult stage phenotype, non-suppressible by Scer\GAL4^GMR71G10/chic^UAS.cCa

(Yaniv et al., 2020)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Rescued by

ena^Δ151 is rescued by Scer\GAL4^GMR71G10/ena^UAS.D

(Yaniv et al., 2020)

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

ena^Delta151

(Meltzer and Schuldiner, 2020.6.25)

ena^Δ151

(Yaniv et al., 2020)

Name Synonyms

Secondary FlyBase IDs

References (2)

Report Sections

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