FB2024_03 , released June 25, 2024
Allele: Dmel\ovoUASp.A.cHa
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General Information
Symbol
Dmel\ovoUASp.A.cHa
Species
D. melanogaster
Name
FlyBase ID
FBal0358885
Feature type
allele
Associated gene
Dmel\ovo
Associated Insertion(s)
Carried in Construct
P{UASp-ovo.A.H}
Key Links
Transgenic product class
wild_type
(Hayashi et al., 2017)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Hayashi et al., 2017)
Mutagen
in vitro construct
(Hayashi et al., 2017)
Progenitor genotype
Carried in construct
P{UASp-ovo.A.H}
Cytology
Description

UASp regulatory sequences drive expression of the ovo A isoform. The nos 3'UTR is present.

(Hayashi et al., 2017)
Allele components
Component
Use(s)
Regulatory region(s)
UASp
Encoded product / tool
ovo
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Maternal and zygotic expression of ovoUAS.A.cHa under the control of Scer\GAL4VP16.nos.UTR leads to gonads lacking Vasa signal (agametic) and a significant reduction in the number of (normally migrated) female and male germline cells during larval but not embryonic stage when compared to controls.

      Maternal expression of ovoUAS.A.cHa under the control of Scer\GAL4VP16.nos.UTR leads to female but not male gonads lacking Vasa signal (agametic) compared to controls. Also it leads to a significant reduction in the number of female germline cells during embryonic and larval stages whereas it leads to a significant reduction in the number of male germline cells during embryonic and first instar larval stages but not second and third instar larval stages when compared to controls.

      (Hayashi et al., 2017)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Partially rescued by

      ovoUASp.A.cHa is partially rescued by ovoamk

      (Hayashi et al., 2017)
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      ovoUAS.A.cHa
      ovoUASp.A.cHa
      Name Synonyms
      Secondary FlyBase IDs
        References (3)